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- W1967162647 abstract "Leukocyte production is influenced by a family of glycoproteins called colony-stimulating factors. Two of these have been purified, cloned and produced in quantities sufficient for clinical use. Granulocyte colony-stimulating factor (G-CSF) preferentially stimulates neutrophil production and has been shoivn to reduce the duration of neutropenia folloiving chemotherapy. G-CSF therapy also has beneficial effects in a variety of other neutropenic states. Granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates neutrophil, monocyte and eosinophil production and function. GM-CSF is associated with more diverse haematological and clinical effects. George Morstyn and colleagues summarize the promising results from the early clinical trials with these new therapeutic agents." @default.
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- W1967162647 date "1989-04-01" @default.
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- W1967162647 title "Pharmacology of the colony-stimulating factors" @default.
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- W1967162647 doi "https://doi.org/10.1016/0165-6147(89)90168-5" @default.
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