Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967224748> ?p ?o ?g. }
- W1967224748 endingPage "31" @default.
- W1967224748 startingPage "26" @default.
- W1967224748 abstract "Background and Objectives It was proposed that occult pancreaticobiliary reflux (OPBR) was associated with precancerous mucosal changes in the gallbladder, hence the importance of this disorder. There are no published reports investigating the incidence of OPBR in patients operated on for the entire spectrum of benign gallbladder diseases and gallbladder cancer. Our aim was to determine the incidence of OPBR and measure the levels of active pancreatic enzymes (amylase and lipase) in gallbladder bile of patients undergoing cholecystectomy for benign and malignant gallbladder diseases. Methods One hundred eight patients with normal pancreaticobiliary junction evidenced by operative cholangiography were included in the study. Results According to gallbladder bile amylase and lipase levels, 84.2% and 89% patients respectively had OPBR. OPBR was present in all gallbladder cancer patients; in these patients the biliary levels of amylase and lipase were significantly higher than the levels found in patients with benign gallbladder pathology (P < 0.0001). Conclusions OPBR could lead to inflammatory changes of the biliary epithelium and progress towards the development of precancerous mucosal changes and gallbladder cancer. The reason why such high levels of pancreatic enzymes are regurgitated into the biliary tree of patients with gallbladder cancer should be clarified. J. Surg. Oncol. 2007;96:26–31. © 2007 Wiley-Liss, Inc." @default.
- W1967224748 created "2016-06-24" @default.
- W1967224748 creator A5016553501 @default.
- W1967224748 creator A5031260259 @default.
- W1967224748 creator A5064307340 @default.
- W1967224748 creator A5065115415 @default.
- W1967224748 creator A5073906201 @default.
- W1967224748 creator A5091680495 @default.
- W1967224748 date "2007-01-01" @default.
- W1967224748 modified "2023-10-16" @default.
- W1967224748 title "Occult pancreaticobiliary reflux in gallbladder cancer and benign gallbladder diseases" @default.
- W1967224748 cites W1525027266 @default.
- W1967224748 cites W1542180446 @default.
- W1967224748 cites W1963572413 @default.
- W1967224748 cites W1968271621 @default.
- W1967224748 cites W1969636888 @default.
- W1967224748 cites W1971594416 @default.
- W1967224748 cites W1973683517 @default.
- W1967224748 cites W1987992381 @default.
- W1967224748 cites W1993271841 @default.
- W1967224748 cites W1993970839 @default.
- W1967224748 cites W1996942810 @default.
- W1967224748 cites W2003158814 @default.
- W1967224748 cites W2005222865 @default.
- W1967224748 cites W2008401658 @default.
- W1967224748 cites W2013661585 @default.
- W1967224748 cites W2031659178 @default.
- W1967224748 cites W2035243666 @default.
- W1967224748 cites W2039831592 @default.
- W1967224748 cites W2050563506 @default.
- W1967224748 cites W2065918303 @default.
- W1967224748 cites W2066039106 @default.
- W1967224748 cites W2066947256 @default.
- W1967224748 cites W2074878542 @default.
- W1967224748 cites W2077394048 @default.
- W1967224748 cites W2080898875 @default.
- W1967224748 cites W2093232874 @default.
- W1967224748 cites W2094549591 @default.
- W1967224748 cites W2095792480 @default.
- W1967224748 cites W2116926537 @default.
- W1967224748 cites W2136123934 @default.
- W1967224748 cites W2145940568 @default.
- W1967224748 cites W2318728811 @default.
- W1967224748 cites W4301432394 @default.
- W1967224748 doi "https://doi.org/10.1002/jso.20756" @default.
- W1967224748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17345616" @default.
- W1967224748 hasPublicationYear "2007" @default.
- W1967224748 type Work @default.
- W1967224748 sameAs 1967224748 @default.
- W1967224748 citedByCount "31" @default.
- W1967224748 countsByYear W19672247482012 @default.
- W1967224748 countsByYear W19672247482013 @default.
- W1967224748 countsByYear W19672247482014 @default.
- W1967224748 countsByYear W19672247482015 @default.
- W1967224748 countsByYear W19672247482016 @default.
- W1967224748 countsByYear W19672247482017 @default.
- W1967224748 countsByYear W19672247482018 @default.
- W1967224748 countsByYear W19672247482020 @default.
- W1967224748 countsByYear W19672247482021 @default.
- W1967224748 countsByYear W19672247482022 @default.
- W1967224748 countsByYear W19672247482023 @default.
- W1967224748 crossrefType "journal-article" @default.
- W1967224748 hasAuthorship W1967224748A5016553501 @default.
- W1967224748 hasAuthorship W1967224748A5031260259 @default.
- W1967224748 hasAuthorship W1967224748A5064307340 @default.
- W1967224748 hasAuthorship W1967224748A5065115415 @default.
- W1967224748 hasAuthorship W1967224748A5073906201 @default.
- W1967224748 hasAuthorship W1967224748A5091680495 @default.
- W1967224748 hasConcept C120665830 @default.
- W1967224748 hasConcept C121332964 @default.
- W1967224748 hasConcept C121608353 @default.
- W1967224748 hasConcept C126322002 @default.
- W1967224748 hasConcept C2776493420 @default.
- W1967224748 hasConcept C2776534502 @default.
- W1967224748 hasConcept C2776641081 @default.
- W1967224748 hasConcept C2777148285 @default.
- W1967224748 hasConcept C61511704 @default.
- W1967224748 hasConcept C71924100 @default.
- W1967224748 hasConcept C90924648 @default.
- W1967224748 hasConceptScore W1967224748C120665830 @default.
- W1967224748 hasConceptScore W1967224748C121332964 @default.
- W1967224748 hasConceptScore W1967224748C121608353 @default.
- W1967224748 hasConceptScore W1967224748C126322002 @default.
- W1967224748 hasConceptScore W1967224748C2776493420 @default.
- W1967224748 hasConceptScore W1967224748C2776534502 @default.
- W1967224748 hasConceptScore W1967224748C2776641081 @default.
- W1967224748 hasConceptScore W1967224748C2777148285 @default.
- W1967224748 hasConceptScore W1967224748C61511704 @default.
- W1967224748 hasConceptScore W1967224748C71924100 @default.
- W1967224748 hasConceptScore W1967224748C90924648 @default.
- W1967224748 hasIssue "1" @default.
- W1967224748 hasLocation W19672247481 @default.
- W1967224748 hasLocation W19672247482 @default.
- W1967224748 hasOpenAccess W1967224748 @default.
- W1967224748 hasPrimaryLocation W19672247481 @default.
- W1967224748 hasRelatedWork W1490679799 @default.
- W1967224748 hasRelatedWork W1511958754 @default.
- W1967224748 hasRelatedWork W2080913653 @default.