Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967249166> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1967249166 endingPage "542" @default.
- W1967249166 startingPage "531" @default.
- W1967249166 abstract "Abstract Models of the incubation period of anthrax are important to public health planners because they can be used to predict the delay before outbreaks are detected, the size of an outbreak and the duration of time that persons should remain on antibiotics to prevent disease. The difficulty is that there is little direct data about the incubation period in humans. The objective of this paper is to develop and apply models for the incubation period of anthrax. Mechanistic models that account for the biology of spore clearance and germination are developed based on a competing risks formulation. The models predict that the incubation period distribution depends critically on the rate that spores are cleared from the lung and to a lesser extent on the dose of inhaled spores. The models are used in a statistical analysis of data from an anthrax outbreak that occurred in Sverdlovsk, Russia. The analysis suggests that spores are cleared from the lung at a rate between 8 per cent per day and 14 per cent per day, which is in good agreement with experimental studies of animals. The analysis suggests that at low doses, the overall median incubation period time is about 10 days, which includes a median lag of about 2 days between spore germination and onset of symptoms. Male gender and younger ages were associated with longer incubation periods as was lower dose of inhaled spores. Copyright © 2005 John Wiley & Sons, Ltd." @default.
- W1967249166 created "2016-06-24" @default.
- W1967249166 creator A5047859114 @default.
- W1967249166 creator A5073783403 @default.
- W1967249166 creator A5075223867 @default.
- W1967249166 date "2005-01-28" @default.
- W1967249166 modified "2023-09-30" @default.
- W1967249166 title "Modelling the incubation period of anthrax" @default.
- W1967249166 cites W1981050209 @default.
- W1967249166 cites W2000171430 @default.
- W1967249166 cites W2002067306 @default.
- W1967249166 cites W2014662468 @default.
- W1967249166 cites W2049236196 @default.
- W1967249166 cites W2066923884 @default.
- W1967249166 cites W2084069113 @default.
- W1967249166 cites W2103828083 @default.
- W1967249166 cites W2107309474 @default.
- W1967249166 cites W2107562550 @default.
- W1967249166 cites W2143225615 @default.
- W1967249166 cites W2153553307 @default.
- W1967249166 cites W2153922590 @default.
- W1967249166 cites W2316920540 @default.
- W1967249166 cites W4238652022 @default.
- W1967249166 doi "https://doi.org/10.1002/sim.2033" @default.
- W1967249166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15678407" @default.
- W1967249166 hasPublicationYear "2005" @default.
- W1967249166 type Work @default.
- W1967249166 sameAs 1967249166 @default.
- W1967249166 citedByCount "69" @default.
- W1967249166 countsByYear W19672491662012 @default.
- W1967249166 countsByYear W19672491662013 @default.
- W1967249166 countsByYear W19672491662014 @default.
- W1967249166 countsByYear W19672491662015 @default.
- W1967249166 countsByYear W19672491662016 @default.
- W1967249166 countsByYear W19672491662017 @default.
- W1967249166 countsByYear W19672491662018 @default.
- W1967249166 countsByYear W19672491662019 @default.
- W1967249166 countsByYear W19672491662020 @default.
- W1967249166 countsByYear W19672491662021 @default.
- W1967249166 countsByYear W19672491662022 @default.
- W1967249166 countsByYear W19672491662023 @default.
- W1967249166 crossrefType "journal-article" @default.
- W1967249166 hasAuthorship W1967249166A5047859114 @default.
- W1967249166 hasAuthorship W1967249166A5073783403 @default.
- W1967249166 hasAuthorship W1967249166A5075223867 @default.
- W1967249166 hasConcept C116675565 @default.
- W1967249166 hasConcept C126894567 @default.
- W1967249166 hasConcept C138944611 @default.
- W1967249166 hasConcept C143701427 @default.
- W1967249166 hasConcept C159047783 @default.
- W1967249166 hasConcept C174618031 @default.
- W1967249166 hasConcept C186060115 @default.
- W1967249166 hasConcept C25642318 @default.
- W1967249166 hasConcept C2993377847 @default.
- W1967249166 hasConcept C33070731 @default.
- W1967249166 hasConcept C42972112 @default.
- W1967249166 hasConcept C55493867 @default.
- W1967249166 hasConcept C71924100 @default.
- W1967249166 hasConcept C86803240 @default.
- W1967249166 hasConcept C89423630 @default.
- W1967249166 hasConceptScore W1967249166C116675565 @default.
- W1967249166 hasConceptScore W1967249166C126894567 @default.
- W1967249166 hasConceptScore W1967249166C138944611 @default.
- W1967249166 hasConceptScore W1967249166C143701427 @default.
- W1967249166 hasConceptScore W1967249166C159047783 @default.
- W1967249166 hasConceptScore W1967249166C174618031 @default.
- W1967249166 hasConceptScore W1967249166C186060115 @default.
- W1967249166 hasConceptScore W1967249166C25642318 @default.
- W1967249166 hasConceptScore W1967249166C2993377847 @default.
- W1967249166 hasConceptScore W1967249166C33070731 @default.
- W1967249166 hasConceptScore W1967249166C42972112 @default.
- W1967249166 hasConceptScore W1967249166C55493867 @default.
- W1967249166 hasConceptScore W1967249166C71924100 @default.
- W1967249166 hasConceptScore W1967249166C86803240 @default.
- W1967249166 hasConceptScore W1967249166C89423630 @default.
- W1967249166 hasIssue "4" @default.
- W1967249166 hasLocation W19672491661 @default.
- W1967249166 hasLocation W19672491662 @default.
- W1967249166 hasOpenAccess W1967249166 @default.
- W1967249166 hasPrimaryLocation W19672491661 @default.
- W1967249166 hasRelatedWork W1967249166 @default.
- W1967249166 hasRelatedWork W2056078382 @default.
- W1967249166 hasRelatedWork W2063309071 @default.
- W1967249166 hasRelatedWork W2128355775 @default.
- W1967249166 hasRelatedWork W2170253009 @default.
- W1967249166 hasRelatedWork W2326317395 @default.
- W1967249166 hasRelatedWork W2393787079 @default.
- W1967249166 hasRelatedWork W2786639540 @default.
- W1967249166 hasRelatedWork W307992176 @default.
- W1967249166 hasRelatedWork W2187511211 @default.
- W1967249166 hasVolume "24" @default.
- W1967249166 isParatext "false" @default.
- W1967249166 isRetracted "false" @default.
- W1967249166 magId "1967249166" @default.
- W1967249166 workType "article" @default.