Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967311529> ?p ?o ?g. }
- W1967311529 endingPage "1403" @default.
- W1967311529 startingPage "1396" @default.
- W1967311529 abstract "Immune cells and skeletal muscle express Toll-like receptors (TLRs) that participate as sensors of tissue injury triggering signals for activation of innate and adaptive immune responses. This study aimed to investigate the involvement of TLR4 in the process of skeletal muscle repair. Muscular injury was induced by injection of 0.6 mg/kg of Bothrops jararacussu snake venom in the gastrocnemius muscle of C3H/HeJ mice that express a non-functional TLR-4 receptor and C3H/HeN mice with functional receptor. TLR4-deficient mice had persistent muscular inflammation with few F4/80 macrophages at onset but increased MMP9 activity and collagen deposition during resolution of injury. Since such effect was not observed in the mouse strain with functional receptor it is concluded that TLR4 signaling exerts a protective role preventing from excessive muscular damage induced by B. jararacussu venom." @default.
- W1967311529 created "2016-06-24" @default.
- W1967311529 creator A5008853058 @default.
- W1967311529 creator A5009375543 @default.
- W1967311529 creator A5011319594 @default.
- W1967311529 creator A5049800991 @default.
- W1967311529 creator A5072339196 @default.
- W1967311529 creator A5083179522 @default.
- W1967311529 date "2012-12-01" @default.
- W1967311529 modified "2023-10-18" @default.
- W1967311529 title "TLR4 signaling protects from excessive muscular damage induced by Bothrops jararacussu snake venom" @default.
- W1967311529 cites W1556371511 @default.
- W1967311529 cites W1775749144 @default.
- W1967311529 cites W1968584427 @default.
- W1967311529 cites W1970222129 @default.
- W1967311529 cites W1975185970 @default.
- W1967311529 cites W1982404981 @default.
- W1967311529 cites W1987807884 @default.
- W1967311529 cites W1990420775 @default.
- W1967311529 cites W1990870153 @default.
- W1967311529 cites W1993792235 @default.
- W1967311529 cites W1994787439 @default.
- W1967311529 cites W2015348280 @default.
- W1967311529 cites W2017283877 @default.
- W1967311529 cites W2017429680 @default.
- W1967311529 cites W2028491403 @default.
- W1967311529 cites W2029727330 @default.
- W1967311529 cites W2033052999 @default.
- W1967311529 cites W2039784479 @default.
- W1967311529 cites W2041013937 @default.
- W1967311529 cites W2045098547 @default.
- W1967311529 cites W2048261486 @default.
- W1967311529 cites W2049051001 @default.
- W1967311529 cites W2050405000 @default.
- W1967311529 cites W2056567384 @default.
- W1967311529 cites W2068445992 @default.
- W1967311529 cites W2072115152 @default.
- W1967311529 cites W2079831464 @default.
- W1967311529 cites W2086331409 @default.
- W1967311529 cites W2093081515 @default.
- W1967311529 cites W2109491705 @default.
- W1967311529 cites W2126472646 @default.
- W1967311529 cites W2127335531 @default.
- W1967311529 cites W2129319296 @default.
- W1967311529 cites W2133523105 @default.
- W1967311529 cites W2136293998 @default.
- W1967311529 cites W2141291906 @default.
- W1967311529 cites W2141801137 @default.
- W1967311529 cites W2152997804 @default.
- W1967311529 cites W2164714222 @default.
- W1967311529 cites W2167537804 @default.
- W1967311529 doi "https://doi.org/10.1016/j.toxicon.2012.10.003" @default.
- W1967311529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23085424" @default.
- W1967311529 hasPublicationYear "2012" @default.
- W1967311529 type Work @default.
- W1967311529 sameAs 1967311529 @default.
- W1967311529 citedByCount "13" @default.
- W1967311529 countsByYear W19673115292016 @default.
- W1967311529 countsByYear W19673115292017 @default.
- W1967311529 countsByYear W19673115292018 @default.
- W1967311529 countsByYear W19673115292019 @default.
- W1967311529 countsByYear W19673115292022 @default.
- W1967311529 countsByYear W19673115292023 @default.
- W1967311529 crossrefType "journal-article" @default.
- W1967311529 hasAuthorship W1967311529A5008853058 @default.
- W1967311529 hasAuthorship W1967311529A5009375543 @default.
- W1967311529 hasAuthorship W1967311529A5011319594 @default.
- W1967311529 hasAuthorship W1967311529A5049800991 @default.
- W1967311529 hasAuthorship W1967311529A5072339196 @default.
- W1967311529 hasAuthorship W1967311529A5083179522 @default.
- W1967311529 hasBestOaLocation W19673115291 @default.
- W1967311529 hasConcept C126322002 @default.
- W1967311529 hasConcept C134018914 @default.
- W1967311529 hasConcept C170493617 @default.
- W1967311529 hasConcept C203014093 @default.
- W1967311529 hasConcept C2776070231 @default.
- W1967311529 hasConcept C2776725428 @default.
- W1967311529 hasConcept C2776914184 @default.
- W1967311529 hasConcept C2779448229 @default.
- W1967311529 hasConcept C2779815518 @default.
- W1967311529 hasConcept C2779959927 @default.
- W1967311529 hasConcept C55493867 @default.
- W1967311529 hasConcept C71924100 @default.
- W1967311529 hasConcept C86803240 @default.
- W1967311529 hasConcept C8891405 @default.
- W1967311529 hasConcept C98274493 @default.
- W1967311529 hasConceptScore W1967311529C126322002 @default.
- W1967311529 hasConceptScore W1967311529C134018914 @default.
- W1967311529 hasConceptScore W1967311529C170493617 @default.
- W1967311529 hasConceptScore W1967311529C203014093 @default.
- W1967311529 hasConceptScore W1967311529C2776070231 @default.
- W1967311529 hasConceptScore W1967311529C2776725428 @default.
- W1967311529 hasConceptScore W1967311529C2776914184 @default.
- W1967311529 hasConceptScore W1967311529C2779448229 @default.
- W1967311529 hasConceptScore W1967311529C2779815518 @default.
- W1967311529 hasConceptScore W1967311529C2779959927 @default.
- W1967311529 hasConceptScore W1967311529C55493867 @default.
- W1967311529 hasConceptScore W1967311529C71924100 @default.