FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967316125> ?p ?o ?g. }

• W1967316125 endingPage "45" @default.
• W1967316125 startingPage "39" @default.
• W1967316125 abstract "Sulfur mustard (bis(2-chloroethyl) sulfide, SM), a chemical warfare agent, is classified as a class I human carcinogen by IARC. No effective antidote against this agent is available. The synthetic aminothiol, amifostine, earlier known as WR-2721, has been extensively used as a chemical radioprotector for normal tissues in cancer radiotherapy and chemotherapy. SM is a radiomimetic agent; this prompted us to evaluate the protective efficacy of amifostine and three of its analogs, DRDE-07 [S-2(2-aminoethylamino) ethyl phenyl sulphide], DRDE-30 [S-2(2-aminoethyl amino) ethyl propyl sulphide] and DRDE-35 [S-2(2-aminoethyl amino) ethyl butyl sulphide], against sulfur mustard-induced mutagenicity in the Ames Salmonella/microsome assay. The antidotes were also evaluated for possible mutagenic activity. DRDE-07 was mutagenic in strain TA104 in the absence of S9; DRDE-30 was mutagenic in strain TA100; amifostine and DRDE-35 did not show mutagenic activity in any of the five tester strains used. SM is mutagenic in strains TA97a and TA102, with or without S9 activation. In the antimutagenicity studies, DRDE-07 and DRDE-35 showed promising antimutagenic activity against SM in the absence of S9, in comparison to amifostine. DRDE-07 and DRDE-35 are promising protective agents against SM-induced mutagenicity." @default.
• W1967316125 created "2016-06-24" @default.
• W1967316125 creator A5003996339 @default.
• W1967316125 creator A5051287931 @default.
• W1967316125 creator A5084637051 @default.
• W1967316125 date "2014-10-01" @default.
• W1967316125 modified "2023-10-01" @default.
• W1967316125 title "Mutagenicity and antimutagenicity studies of DRDE-07 and its analogs against sulfur mustard in the in vitro Ames Salmonella/microsome assay" @default.
• W1967316125 cites W1973195696 @default.
• W1967316125 cites W1984648029 @default.
• W1967316125 cites W1984691496 @default.
• W1967316125 cites W1986900956 @default.
• W1967316125 cites W1987167155 @default.
• W1967316125 cites W1988988065 @default.
• W1967316125 cites W1989817404 @default.
• W1967316125 cites W1991833718 @default.
• W1967316125 cites W2002283777 @default.
• W1967316125 cites W2005156172 @default.
• W1967316125 cites W2009451331 @default.
• W1967316125 cites W2013984864 @default.
• W1967316125 cites W2021001823 @default.
• W1967316125 cites W2023992546 @default.
• W1967316125 cites W2044949614 @default.
• W1967316125 cites W2049959729 @default.
• W1967316125 cites W2059975377 @default.
• W1967316125 cites W2062962676 @default.
• W1967316125 cites W2063690381 @default.
• W1967316125 cites W2078030319 @default.
• W1967316125 cites W2090485206 @default.
• W1967316125 cites W2091111181 @default.
• W1967316125 cites W2092709582 @default.
• W1967316125 cites W2099342380 @default.
• W1967316125 cites W2105966380 @default.
• W1967316125 cites W2144366763 @default.
• W1967316125 cites W224884715 @default.
• W1967316125 doi "https://doi.org/10.1016/j.mrgentox.2014.08.003" @default.
• W1967316125 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25308705" @default.
• W1967316125 hasPublicationYear "2014" @default.
• W1967316125 type Work @default.
• W1967316125 sameAs 1967316125 @default.
• W1967316125 citedByCount "6" @default.
• W1967316125 countsByYear W19673161252015 @default.
• W1967316125 countsByYear W19673161252016 @default.
• W1967316125 countsByYear W19673161252018 @default.
• W1967316125 countsByYear W19673161252019 @default.
• W1967316125 crossrefType "journal-article" @default.
• W1967316125 hasAuthorship W1967316125A5003996339 @default.
• W1967316125 hasAuthorship W1967316125A5051287931 @default.
• W1967316125 hasAuthorship W1967316125A5084637051 @default.
• W1967316125 hasConcept C114246631 @default.
• W1967316125 hasConcept C117632636 @default.
• W1967316125 hasConcept C178790620 @default.
• W1967316125 hasConcept C185592680 @default.
• W1967316125 hasConcept C202751555 @default.
• W1967316125 hasConcept C2779365888 @default.
• W1967316125 hasConcept C2779387952 @default.
• W1967316125 hasConcept C2780644109 @default.
• W1967316125 hasConcept C2781065037 @default.
• W1967316125 hasConcept C29730261 @default.
• W1967316125 hasConcept C33070731 @default.
• W1967316125 hasConcept C518881349 @default.
• W1967316125 hasConcept C523546767 @default.
• W1967316125 hasConcept C54355233 @default.
• W1967316125 hasConcept C55493867 @default.
• W1967316125 hasConcept C86803240 @default.
• W1967316125 hasConcept C87644729 @default.
• W1967316125 hasConcept C98274493 @default.
• W1967316125 hasConceptScore W1967316125C114246631 @default.
• W1967316125 hasConceptScore W1967316125C117632636 @default.
• W1967316125 hasConceptScore W1967316125C178790620 @default.
• W1967316125 hasConceptScore W1967316125C185592680 @default.
• W1967316125 hasConceptScore W1967316125C202751555 @default.
• W1967316125 hasConceptScore W1967316125C2779365888 @default.
• W1967316125 hasConceptScore W1967316125C2779387952 @default.
• W1967316125 hasConceptScore W1967316125C2780644109 @default.
• W1967316125 hasConceptScore W1967316125C2781065037 @default.
• W1967316125 hasConceptScore W1967316125C29730261 @default.
• W1967316125 hasConceptScore W1967316125C33070731 @default.
• W1967316125 hasConceptScore W1967316125C518881349 @default.
• W1967316125 hasConceptScore W1967316125C523546767 @default.
• W1967316125 hasConceptScore W1967316125C54355233 @default.
• W1967316125 hasConceptScore W1967316125C55493867 @default.
• W1967316125 hasConceptScore W1967316125C86803240 @default.
• W1967316125 hasConceptScore W1967316125C87644729 @default.
• W1967316125 hasConceptScore W1967316125C98274493 @default.
• W1967316125 hasLocation W19673161251 @default.
• W1967316125 hasLocation W19673161252 @default.
• W1967316125 hasOpenAccess W1967316125 @default.
• W1967316125 hasPrimaryLocation W19673161251 @default.
• W1967316125 hasRelatedWork W1967316125 @default.
• W1967316125 hasRelatedWork W1995148557 @default.
• W1967316125 hasRelatedWork W2028919094 @default.
• W1967316125 hasRelatedWork W2037060949 @default.
• W1967316125 hasRelatedWork W2041626709 @default.
• W1967316125 hasRelatedWork W2290909658 @default.
• W1967316125 hasRelatedWork W2410414887 @default.
• W1967316125 hasRelatedWork W299641249 @default.
• W1967316125 hasRelatedWork W4360976703 @default.

• next