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- W1967341331 abstract "SummaryBy the modified method of ion exchange resin chromatography of Hurlbert et al, which is designed to perform fractionation in a short time with relatively simple instruments, the brain acid-soluble nucleotide of albino rats were seperated and measured. Under the condition of freezing animals with dropping of liquid air, adenine nucleotide accounted for about 70 % of all nucleotide, and ATP, ADP, AMP were each 0.55, 0.37, 0.36/xM per wet gram of the brain, ATP/ADP being 1.49. nucleotide polyphosphate, especially ATP, were decomposed soon after the death of animals to get vanished at about 30 minutes, while the decrease of ADP was slower than that of ATP.As the result of investigation on the cerebral phosphorus metabolism utilizing P32 in ion exchange resin chromatography, it proved that P32 was rapidly incorporated into the labile-P such as ATP and ADP in case of subaraehnoideal P32 injection with about the same speed as in case of the liver. The main reason why the turn-over from inorganic phosphorus to ATP and ADP was delayed apparently in the case of intraperitoneal P32 injection consists presumably in the unavoidable blood interfusion into the brain in cases of freezing and extraction." @default.
- W1967341331 created "2016-06-24" @default.
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- W1967341331 date "1961-07-01" @default.
- W1967341331 modified "2023-09-24" @default.
- W1967341331 title "ION EXCHANGE CHROMATOGRAPHIC STUDIES ON ACID-SOLUBLE BRAIN NUCLEOTIDES AND INCORPORATION OF P32INTO THEM" @default.
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- W1967341331 doi "https://doi.org/10.1111/j.1440-1819.1961.tb00640.x" @default.
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