FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967345282> ?p ?o ?g. }

• W1967345282 endingPage "614" @default.
• W1967345282 startingPage "607" @default.
• W1967345282 abstract "Context: Antiretroviral therapy has been associated with hypercholesterolemia in HIV-infected children. Few longitudinal studies have been conducted to examine this association, however. Objective: To evaluate the incidence of and risk factors for development of hypercholesterolemia in a large pediatric study. Design: Prospective cohort study (Pediatric AIDS Clinical Trials Group 219C). Participants: A total of 2122 perinatally HIV-infected children free of hypercholesterolemia at entry. Outcome: Development of hypercholesterolemia (total cholesterol ≥220 mg/dL at 2 consecutive visits). Cox proportional hazards models were used to evaluate risk factors. Results: Thirteen percent of children had hypercholesterolemia at entry, and an additional 13% developed hypercholesterolemia during follow-up for an incidence rate of 3.4 cases per 100 person-years (95% confidence interval [CI]: 3.0 to 3.9). After adjustment for age, boosted protease inhibitor (PI) use (hazard ratio [HR] = 13.9, 95% CI: 6.73 to 28.6), nonboosted PI use (HR = 8.65, 95% CI: 4.19 to 17.9), and nonnucleoside reverse transcriptase inhibitor use (HR = 1.33, 95% CI: 1.04 to 1.71) were associated with increased risk of hypercholesterolemia, and higher viral load was protective (>50,000 vs. ≤400 copies/mL; HR = 0.59, 95% CI: 0.39 to 0.90). Self-reported adherent subjects had higher risk. Conclusions: PIs were significant risk factors for hypercholesterolemia. Higher viral load was protective and may reflect nonadherence. Further follow-up is critical to evaluate long-term consequences of chronic PI exposure and hypercholesterolemia." @default.
• W1967345282 created "2016-06-24" @default.
• W1967345282 creator A5002712707 @default.
• W1967345282 creator A5030452461 @default.
• W1967345282 creator A5034030812 @default.
• W1967345282 creator A5035006251 @default.
• W1967345282 creator A5038269182 @default.
• W1967345282 creator A5084075693 @default.
• W1967345282 date "2008-04-15" @default.
• W1967345282 modified "2023-09-26" @default.
• W1967345282 title "Association of Hypercholesterolemia Incidence With Antiretroviral Treatment, Including Protease Inhibitors, Among Perinatally HIV-Infected Children" @default.
• W1967345282 cites W1958444278 @default.
• W1967345282 cites W1965153851 @default.
• W1967345282 cites W1968461165 @default.
• W1967345282 cites W1971771720 @default.
• W1967345282 cites W1976022560 @default.
• W1967345282 cites W1981937271 @default.
• W1967345282 cites W1994477876 @default.
• W1967345282 cites W2001969007 @default.
• W1967345282 cites W2004027480 @default.
• W1967345282 cites W2007061668 @default.
• W1967345282 cites W2010178853 @default.
• W1967345282 cites W2015491389 @default.
• W1967345282 cites W2028657303 @default.
• W1967345282 cites W2030429103 @default.
• W1967345282 cites W2043734824 @default.
• W1967345282 cites W2045131275 @default.
• W1967345282 cites W2070344375 @default.
• W1967345282 cites W2071909247 @default.
• W1967345282 cites W2076768567 @default.
• W1967345282 cites W2077590295 @default.
• W1967345282 cites W2078197243 @default.
• W1967345282 cites W2089032846 @default.
• W1967345282 cites W2090963139 @default.
• W1967345282 cites W2118964190 @default.
• W1967345282 cites W2135032077 @default.
• W1967345282 cites W2137569461 @default.
• W1967345282 cites W2142541558 @default.
• W1967345282 cites W2152344035 @default.
• W1967345282 cites W2163617802 @default.
• W1967345282 cites W2168784348 @default.
• W1967345282 cites W2325164377 @default.
• W1967345282 cites W2336250349 @default.
• W1967345282 cites W4238251256 @default.
• W1967345282 cites W4251533006 @default.
• W1967345282 doi "https://doi.org/10.1097/qai.0b013e3181648e16" @default.
• W1967345282 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3089963" @default.
• W1967345282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18209684" @default.
• W1967345282 hasPublicationYear "2008" @default.
• W1967345282 type Work @default.
• W1967345282 sameAs 1967345282 @default.
• W1967345282 citedByCount "54" @default.
• W1967345282 countsByYear W19673452822012 @default.
• W1967345282 countsByYear W19673452822013 @default.
• W1967345282 countsByYear W19673452822014 @default.
• W1967345282 countsByYear W19673452822015 @default.
• W1967345282 countsByYear W19673452822016 @default.
• W1967345282 countsByYear W19673452822017 @default.
• W1967345282 countsByYear W19673452822018 @default.
• W1967345282 countsByYear W19673452822019 @default.
• W1967345282 countsByYear W19673452822020 @default.
• W1967345282 countsByYear W19673452822021 @default.
• W1967345282 countsByYear W19673452822022 @default.
• W1967345282 crossrefType "journal-article" @default.
• W1967345282 hasAuthorship W1967345282A5002712707 @default.
• W1967345282 hasAuthorship W1967345282A5030452461 @default.
• W1967345282 hasAuthorship W1967345282A5034030812 @default.
• W1967345282 hasAuthorship W1967345282A5035006251 @default.
• W1967345282 hasAuthorship W1967345282A5038269182 @default.
• W1967345282 hasAuthorship W1967345282A5084075693 @default.
• W1967345282 hasBestOaLocation W19673452821 @default.
• W1967345282 hasConcept C120665830 @default.
• W1967345282 hasConcept C121332964 @default.
• W1967345282 hasConcept C126322002 @default.
• W1967345282 hasConcept C142462285 @default.
• W1967345282 hasConcept C151730666 @default.
• W1967345282 hasConcept C188816634 @default.
• W1967345282 hasConcept C201903717 @default.
• W1967345282 hasConcept C203014093 @default.
• W1967345282 hasConcept C207103383 @default.
• W1967345282 hasConcept C2779343474 @default.
• W1967345282 hasConcept C3013748606 @default.
• W1967345282 hasConcept C44249647 @default.
• W1967345282 hasConcept C50382708 @default.
• W1967345282 hasConcept C50440223 @default.
• W1967345282 hasConcept C61511704 @default.
• W1967345282 hasConcept C71924100 @default.
• W1967345282 hasConcept C86803240 @default.
• W1967345282 hasConceptScore W1967345282C120665830 @default.
• W1967345282 hasConceptScore W1967345282C121332964 @default.
• W1967345282 hasConceptScore W1967345282C126322002 @default.
• W1967345282 hasConceptScore W1967345282C142462285 @default.
• W1967345282 hasConceptScore W1967345282C151730666 @default.
• W1967345282 hasConceptScore W1967345282C188816634 @default.
• W1967345282 hasConceptScore W1967345282C201903717 @default.
• W1967345282 hasConceptScore W1967345282C203014093 @default.
• W1967345282 hasConceptScore W1967345282C207103383 @default.
• W1967345282 hasConceptScore W1967345282C2779343474 @default.

• next