FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967428323> ?p ?o ?g. }

• W1967428323 endingPage "1085" @default.
• W1967428323 startingPage "1078" @default.
• W1967428323 abstract "To explore the effects of plasma containing Buyang Huanwu Decoction (BYHWD), a compound of traditional Chinese medicine, and its effective components (alkaloids and glycosides) and total Panax notoginseng saponins (TSPN) on vascular smooth muscle cell (VSMC) proliferation induced by platelet-derived growth factor (PDGF) in vitro.VSMC proliferation was induced by incubating VSMCs with PDGF-BB. Effects of different concentrations of blank plasma on the VSMC proliferation and 50% inhibitory concentrations of plasma containing BYHWD, its alkaloids and glycosides, TSPN and atorvastatin were detected by using methyl thiazolyl tetrazolium (MTT) method to determine the concentrations of plasma containing drugs for the following experiments. Then, MTT and flow cytometry methods were used to detect the effects of plasma containing BYHWD, its alkaloids and glycosides, TSPN and atorvastatin on VSMC proliferative activity and cell cycles.VSMC proliferative activity was enhanced obviously after PDGF-BB stimulation. The cell number in G(0)/G(1) phase was decreased and the cell quantity in G(2)/M and S phases was increased following PDGF-BB stimulation. Compared with PDGF-BB stimulation group, VSMC proliferation induced by PDGF-BB in plasma containing BYHWD, its alkaloids and glycosides, TSPN and atorvastatin groups was inhibited. In all plasma containing drug components groups, the cell number of G(0)/G(1) phase was higher and the cell quantity of G(2)/M and S phases was lower than those in the PDGF-BB stimulation group.BYHWD and its alkaloids and glycosides have similar roles of resisting VSMC proliferation to TSPN and atorvastatin. Alkaloids and glycosides may be the major effective substances of anti-VSMC proliferation in BYHWD." @default.
• W1967428323 created "2016-06-24" @default.
• W1967428323 creator A5017803442 @default.
• W1967428323 creator A5024040305 @default.
• W1967428323 creator A5045067652 @default.
• W1967428323 date "2009-11-15" @default.
• W1967428323 modified "2023-10-16" @default.
• W1967428323 title "Effects of plasma containing Buyang Huanwu Decoction and its effective components and total Panax notoginseng saponins on vascular smooth muscle cell proliferation induced by platelet-derived growth factor" @default.
• W1967428323 cites W1975071258 @default.
• W1967428323 cites W1982813557 @default.
• W1967428323 cites W2003431470 @default.
• W1967428323 cites W2023849708 @default.
• W1967428323 cites W2033343821 @default.
• W1967428323 cites W2035284103 @default.
• W1967428323 cites W2047157512 @default.
• W1967428323 cites W2048639618 @default.
• W1967428323 cites W2049203909 @default.
• W1967428323 cites W2079295854 @default.
• W1967428323 cites W2113257943 @default.
• W1967428323 cites W2127310962 @default.
• W1967428323 cites W2127981205 @default.
• W1967428323 cites W2149872984 @default.
• W1967428323 cites W2164390760 @default.
• W1967428323 cites W2357268100 @default.
• W1967428323 cites W2360148472 @default.
• W1967428323 cites W2384844840 @default.
• W1967428323 cites W2397587438 @default.
• W1967428323 cites W2402197600 @default.
• W1967428323 cites W44169799 @default.
• W1967428323 doi "https://doi.org/10.3736/jcim20091111" @default.
• W1967428323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19912742" @default.
• W1967428323 hasPublicationYear "2009" @default.
• W1967428323 type Work @default.
• W1967428323 sameAs 1967428323 @default.
• W1967428323 citedByCount "6" @default.
• W1967428323 countsByYear W19674283232013 @default.
• W1967428323 countsByYear W19674283232016 @default.
• W1967428323 crossrefType "journal-article" @default.
• W1967428323 hasAuthorship W1967428323A5017803442 @default.
• W1967428323 hasAuthorship W1967428323A5024040305 @default.
• W1967428323 hasAuthorship W1967428323A5045067652 @default.
• W1967428323 hasConcept C134018914 @default.
• W1967428323 hasConcept C142724271 @default.
• W1967428323 hasConcept C170493617 @default.
• W1967428323 hasConcept C180361614 @default.
• W1967428323 hasConcept C185592680 @default.
• W1967428323 hasConcept C190409667 @default.
• W1967428323 hasConcept C194671627 @default.
• W1967428323 hasConcept C204787440 @default.
• W1967428323 hasConcept C24998067 @default.
• W1967428323 hasConcept C2775960820 @default.
• W1967428323 hasConcept C2779395532 @default.
• W1967428323 hasConcept C2781212864 @default.
• W1967428323 hasConcept C2992686903 @default.
• W1967428323 hasConcept C55493867 @default.
• W1967428323 hasConcept C556039675 @default.
• W1967428323 hasConcept C62112901 @default.
• W1967428323 hasConcept C71240020 @default.
• W1967428323 hasConcept C71924100 @default.
• W1967428323 hasConcept C86803240 @default.
• W1967428323 hasConcept C98274493 @default.
• W1967428323 hasConceptScore W1967428323C134018914 @default.
• W1967428323 hasConceptScore W1967428323C142724271 @default.
• W1967428323 hasConceptScore W1967428323C170493617 @default.
• W1967428323 hasConceptScore W1967428323C180361614 @default.
• W1967428323 hasConceptScore W1967428323C185592680 @default.
• W1967428323 hasConceptScore W1967428323C190409667 @default.
• W1967428323 hasConceptScore W1967428323C194671627 @default.
• W1967428323 hasConceptScore W1967428323C204787440 @default.
• W1967428323 hasConceptScore W1967428323C24998067 @default.
• W1967428323 hasConceptScore W1967428323C2775960820 @default.
• W1967428323 hasConceptScore W1967428323C2779395532 @default.
• W1967428323 hasConceptScore W1967428323C2781212864 @default.
• W1967428323 hasConceptScore W1967428323C2992686903 @default.
• W1967428323 hasConceptScore W1967428323C55493867 @default.
• W1967428323 hasConceptScore W1967428323C556039675 @default.
• W1967428323 hasConceptScore W1967428323C62112901 @default.
• W1967428323 hasConceptScore W1967428323C71240020 @default.
• W1967428323 hasConceptScore W1967428323C71924100 @default.
• W1967428323 hasConceptScore W1967428323C86803240 @default.
• W1967428323 hasConceptScore W1967428323C98274493 @default.
• W1967428323 hasIssue "11" @default.
• W1967428323 hasLocation W19674283231 @default.
• W1967428323 hasLocation W19674283232 @default.
• W1967428323 hasOpenAccess W1967428323 @default.
• W1967428323 hasPrimaryLocation W19674283231 @default.
• W1967428323 hasRelatedWork W1963711373 @default.
• W1967428323 hasRelatedWork W2049535510 @default.
• W1967428323 hasRelatedWork W2149200565 @default.
• W1967428323 hasRelatedWork W2355582156 @default.
• W1967428323 hasRelatedWork W2369516964 @default.
• W1967428323 hasRelatedWork W2371437420 @default.
• W1967428323 hasRelatedWork W2386845993 @default.
• W1967428323 hasRelatedWork W2761807471 @default.
• W1967428323 hasRelatedWork W2765685634 @default.
• W1967428323 hasRelatedWork W3154189534 @default.
• W1967428323 hasVolume "7" @default.
• W1967428323 isParatext "false" @default.

• next