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- W1967434234 abstract "Abstract We applied multispacer typing (MST) by incorporating 9 variable intergenic spacers to Bartonella henselae DNA detected in lymph node biopsy specimens from 70 patients with cat-scratch disease (CSD), in cardiac valve specimens from 2 patients with endocarditis, and in 3 human isolates from patients with bacillary angiomatosis, CSD, and endocarditis. Sixteen MST genotypes were found, 5 previously identified in cats and 11 new. Of the studied DNA, 78.7% belonged to 2 genotypes, which were phylogenetically organized into 4 lineages. Human strains were mostly grouped within 2 lineages, previously identified as Marseille and Houston-1. Our results suggest a greater genetic diversity in human-infecting B. henselae than what has previously been evaluated by using other genotyping methods. However, the diversity is not significantly different from that of cat strains. MST is thus a suitable genotyping tool for evaluating the genetic heterogeneity of B. henselae among isolates obtained from human patients." @default.
- W1967434234 created "2016-06-24" @default.
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- W1967434234 date "2007-08-01" @default.
- W1967434234 modified "2023-10-15" @default.
- W1967434234 title "Genetic Diversity of<i>Bartonella henselae</i>in Human Infection Detected with Multispacer Typing" @default.
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- W1967434234 doi "https://doi.org/10.3201/eid1308.070085" @default.
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