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- W1967441301 abstract "Aging is associated with a decline in motor coordination and the ability to learn new motor learning skills. This loss of function is correlated with a decline in cerebellar β-adrenergic receptor function. We have examined the role of oxidative stress on this system by exposing young rats to normobaric hyperoxia. This exogenous oxidative insult results in a decline in cerebellar β-adrenergic receptor function that resembles what is observed in normal aged rats. This effect of hyperoxia is blocked by antioxidants. We have also examined the effects of nutritional supplementation of aged rats with diets high in antioxidant capacity. Foods such as blueberries and spinach can prevent and/or reverse age-related declines in cerebellar noradrenergic receptor function." @default.
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- W1967441301 date "1999-11-01" @default.
- W1967441301 modified "2023-10-17" @default.
- W1967441301 title "Effects of aging on cerebellar noradrenergic function and motor learning: nutritional interventions" @default.
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- W1967441301 doi "https://doi.org/10.1016/s0047-6374(99)00063-9" @default.
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