Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967460273> ?p ?o ?g. }
- W1967460273 endingPage "59" @default.
- W1967460273 startingPage "52" @default.
- W1967460273 abstract "Short-chain fatty acids (SCFA) are produced by microbial fermentation in the hindgut in considerable amounts. Most of the anions in hindgut contents are SCFA, mainly acetate, propionate and butyrate. SCFA are rapidly absorbed. Mechanisms involved in the transepithelial transport are discussed. Besides the contribution to the overall energy metabolism of animals or men, SCFA have a number of further important effects on the colonic mucosa. Factors affecting the pH of compartments in the mucosa, cell swelling, stimulation of mucin release and of mucosal blood flow are mentioned. Controversial reports are known on the role of SCFA in the metabolism of colonocytes. In spite of the conflicting opinions on the interaction between SCFA metabolism and the development of colitis ulcerosa, diverticulosis and colorectal cancer seems to exist. The obscure differences between the effects of SCFA on cell proliferation, differentiation and apoptosis of colonocytes in vivo and in vitro indicate that besides direct effects of SCFA systemic effects such as neural and humoral factors are of crucial importance. The opposing effects of SCFA on proliferation and apoptosis in normal colonocytes and in colonic cancer cells may open possibilities for prevention and/or therapy of patients with colonic diseases." @default.
- W1967460273 created "2016-06-24" @default.
- W1967460273 creator A5009337341 @default.
- W1967460273 creator A5010073083 @default.
- W1967460273 creator A5015958916 @default.
- W1967460273 creator A5028904864 @default.
- W1967460273 creator A5067556112 @default.
- W1967460273 date "1998-06-01" @default.
- W1967460273 modified "2023-10-14" @default.
- W1967460273 title "Role of short‐chain fatty acids in the hind gut" @default.
- W1967460273 cites W101807314 @default.
- W1967460273 cites W1576218825 @default.
- W1967460273 cites W1659460275 @default.
- W1967460273 cites W1752633231 @default.
- W1967460273 cites W1779033144 @default.
- W1967460273 cites W1800141310 @default.
- W1967460273 cites W1837274520 @default.
- W1967460273 cites W1856878777 @default.
- W1967460273 cites W1953702613 @default.
- W1967460273 cites W1956540898 @default.
- W1967460273 cites W1957021685 @default.
- W1967460273 cites W1969595430 @default.
- W1967460273 cites W1970200350 @default.
- W1967460273 cites W1980378896 @default.
- W1967460273 cites W1982062147 @default.
- W1967460273 cites W1984889921 @default.
- W1967460273 cites W1985766240 @default.
- W1967460273 cites W1987076452 @default.
- W1967460273 cites W1991543744 @default.
- W1967460273 cites W1991737476 @default.
- W1967460273 cites W1992932231 @default.
- W1967460273 cites W1995133050 @default.
- W1967460273 cites W1996730950 @default.
- W1967460273 cites W2007748965 @default.
- W1967460273 cites W2008217966 @default.
- W1967460273 cites W2008347160 @default.
- W1967460273 cites W2012349147 @default.
- W1967460273 cites W2016507693 @default.
- W1967460273 cites W2017578044 @default.
- W1967460273 cites W2018831932 @default.
- W1967460273 cites W2018863941 @default.
- W1967460273 cites W2019648419 @default.
- W1967460273 cites W2024684536 @default.
- W1967460273 cites W2030745465 @default.
- W1967460273 cites W2035063007 @default.
- W1967460273 cites W2035177369 @default.
- W1967460273 cites W2037230755 @default.
- W1967460273 cites W2042273036 @default.
- W1967460273 cites W2043025786 @default.
- W1967460273 cites W2044529755 @default.
- W1967460273 cites W2045580159 @default.
- W1967460273 cites W2047492434 @default.
- W1967460273 cites W2048125796 @default.
- W1967460273 cites W2049289120 @default.
- W1967460273 cites W2055454298 @default.
- W1967460273 cites W2058741763 @default.
- W1967460273 cites W2058786461 @default.
- W1967460273 cites W2062277297 @default.
- W1967460273 cites W2069284623 @default.
- W1967460273 cites W2070712215 @default.
- W1967460273 cites W2073934305 @default.
- W1967460273 cites W2075718258 @default.
- W1967460273 cites W2077540881 @default.
- W1967460273 cites W2081966576 @default.
- W1967460273 cites W2093448044 @default.
- W1967460273 cites W2094761693 @default.
- W1967460273 cites W2095870639 @default.
- W1967460273 cites W2098209207 @default.
- W1967460273 cites W2104905032 @default.
- W1967460273 cites W2115396284 @default.
- W1967460273 cites W2126166989 @default.
- W1967460273 cites W2133033066 @default.
- W1967460273 cites W2136821072 @default.
- W1967460273 cites W2146698299 @default.
- W1967460273 cites W2155387655 @default.
- W1967460273 cites W2157318823 @default.
- W1967460273 cites W2158131101 @default.
- W1967460273 cites W2178450581 @default.
- W1967460273 cites W2252816522 @default.
- W1967460273 cites W2321654132 @default.
- W1967460273 cites W2324378182 @default.
- W1967460273 cites W2326201219 @default.
- W1967460273 cites W2341616539 @default.
- W1967460273 cites W2395306627 @default.
- W1967460273 cites W2472139372 @default.
- W1967460273 cites W257289115 @default.
- W1967460273 cites W2619370035 @default.
- W1967460273 cites W83343953 @default.
- W1967460273 cites W93486493 @default.
- W1967460273 cites W2001712597 @default.
- W1967460273 doi "https://doi.org/10.1080/01652176.1998.9694970" @default.
- W1967460273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9689727" @default.
- W1967460273 hasPublicationYear "1998" @default.
- W1967460273 type Work @default.
- W1967460273 sameAs 1967460273 @default.
- W1967460273 citedByCount "84" @default.
- W1967460273 countsByYear W19674602732012 @default.
- W1967460273 countsByYear W19674602732013 @default.