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- W1967479049 abstract "This study evaluated the safety, tolerability, and efficacy of statin therapy in patients with heart failure secondary to inflammatory dilated cardiomyopathy and moderately elevated low-density lipoprotein cholesterol levels. Seventy-four patients were randomized to receive atorvastatin 40 mg/day or conventional treatment for heart failure. After 6 months of therapy, the predefined primary efficacy end point (an increase of >5% in the absolute left ventricular ejection fraction and > or =2 selected criteria by echocardiography and a decrease in New York Heart Association functional class) was significant in the statin-treated patients (p = 0.004). Among secondary efficacy parameters, the quality-of-life index showed a trend suggesting the benefit of statin therapy (p = 0.055). In conclusion, the results of this study demonstrate that treatment with atorvastatin in addition to standard therapy for heart failure may significantly improve clinical outcomes in this cohort of patients." @default.
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- W1967479049 date "2006-03-01" @default.
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- W1967479049 title "Usefulness of Atorvastatin in Patients With Heart Failure Due to Inflammatory Dilated Cardiomyopathy and Elevated Cholesterol Levels" @default.
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- W1967479049 doi "https://doi.org/10.1016/j.amjcard.2005.09.142" @default.
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