FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967485118> ?p ?o ?g. }

• W1967485118 abstract "To define the variations in gastric tone associated with the intestinal motor correlates of vomiting, we studied the effects of intracerebroventricular pharmacological manipulation in four fasting, conscious dogs with an injection catheter implanted into the fourth cerebral ventricle. Simultaneous monitoring of gastric tone and duodenal motility allowed us to study the correlation between gastric and duodenal motor events. We compared the effects of i.c.v. morphine (0.1 to 1 μLg/kg), apomorphine (0.003 to 0.03 (μg/kg), and the α2-adrenoceptor agonist ST91 (0.1 to 1 μg/kg). These agonists, by the i.c.v. route all induced gastric relaxation accompanied by a retrograde power contraction in the duodenum and, at the highest doses, emesis; subsequently, a burst of intense phasic pressure activity developed in the duodenum. However, at a dose that was fully effective i.c.v., they had no effect when given intravenously. Naloxone or domperidone, at doses that had no effect per se, blocked the effects of morphine and apomorphine, respectively, except for a residual gastric relaxation. Idazoxan failed to block the effects of ST91. We conclude that a common pattern of motor events is triggered in the upper gut by different drugs by activation of receptors involved in the mechanism of vomiting and probably located in the central nervous system, and that the effects of morphine and apomorphine are mediated respectively by opioid and dopamine receptors." @default.
• W1967485118 created "2016-06-24" @default.
• W1967485118 creator A5009402989 @default.
• W1967485118 creator A5039483088 @default.
• W1967485118 creator A5042389999 @default.
• W1967485118 creator A5077112229 @default.
• W1967485118 creator A5089491221 @default.
• W1967485118 date "2008-06-28" @default.
• W1967485118 modified "2023-10-18" @default.
• W1967485118 title "Variations in Gastric Tone Associated with Duodenal Motor Events After Activation of Central Emetic Mechanisms in the Dog" @default.
• W1967485118 cites W1561263973 @default.
• W1967485118 cites W1662552656 @default.
• W1967485118 cites W1973155193 @default.
• W1967485118 cites W1976887560 @default.
• W1967485118 cites W1979419703 @default.
• W1967485118 cites W1983205480 @default.
• W1967485118 cites W1989990644 @default.
• W1967485118 cites W2014629907 @default.
• W1967485118 cites W2025894214 @default.
• W1967485118 cites W2051792548 @default.
• W1967485118 cites W2054694308 @default.
• W1967485118 cites W2060222115 @default.
• W1967485118 cites W2060911220 @default.
• W1967485118 cites W2064447763 @default.
• W1967485118 cites W2072678012 @default.
• W1967485118 cites W2074284406 @default.
• W1967485118 cites W2074916786 @default.
• W1967485118 cites W2075011335 @default.
• W1967485118 cites W2086528341 @default.
• W1967485118 cites W2093744068 @default.
• W1967485118 cites W2113279933 @default.
• W1967485118 cites W2236264493 @default.
• W1967485118 cites W2273976413 @default.
• W1967485118 cites W2324665201 @default.
• W1967485118 cites W2410101111 @default.
• W1967485118 cites W4298774499 @default.
• W1967485118 doi "https://doi.org/10.1111/j.1365-2982.1990.tb00001.x" @default.
• W1967485118 hasPublicationYear "2008" @default.
• W1967485118 type Work @default.
• W1967485118 sameAs 1967485118 @default.
• W1967485118 citedByCount "13" @default.
• W1967485118 crossrefType "journal-article" @default.
• W1967485118 hasAuthorship W1967485118A5009402989 @default.
• W1967485118 hasAuthorship W1967485118A5039483088 @default.
• W1967485118 hasAuthorship W1967485118A5042389999 @default.
• W1967485118 hasAuthorship W1967485118A5077112229 @default.
• W1967485118 hasAuthorship W1967485118A5089491221 @default.
• W1967485118 hasConcept C126322002 @default.
• W1967485118 hasConcept C134018914 @default.
• W1967485118 hasConcept C170493617 @default.
• W1967485118 hasConcept C185592680 @default.
• W1967485118 hasConcept C2775995038 @default.
• W1967485118 hasConcept C2776809568 @default.
• W1967485118 hasConcept C2776885963 @default.
• W1967485118 hasConcept C2777389121 @default.
• W1967485118 hasConcept C2777504413 @default.
• W1967485118 hasConcept C2777525119 @default.
• W1967485118 hasConcept C2778938600 @default.
• W1967485118 hasConcept C2779422922 @default.
• W1967485118 hasConcept C2780648677 @default.
• W1967485118 hasConcept C2780852908 @default.
• W1967485118 hasConcept C2780939551 @default.
• W1967485118 hasConcept C42219234 @default.
• W1967485118 hasConcept C513476851 @default.
• W1967485118 hasConcept C55924715 @default.
• W1967485118 hasConcept C71924100 @default.
• W1967485118 hasConceptScore W1967485118C126322002 @default.
• W1967485118 hasConceptScore W1967485118C134018914 @default.
• W1967485118 hasConceptScore W1967485118C170493617 @default.
• W1967485118 hasConceptScore W1967485118C185592680 @default.
• W1967485118 hasConceptScore W1967485118C2775995038 @default.
• W1967485118 hasConceptScore W1967485118C2776809568 @default.
• W1967485118 hasConceptScore W1967485118C2776885963 @default.
• W1967485118 hasConceptScore W1967485118C2777389121 @default.
• W1967485118 hasConceptScore W1967485118C2777504413 @default.
• W1967485118 hasConceptScore W1967485118C2777525119 @default.
• W1967485118 hasConceptScore W1967485118C2778938600 @default.
• W1967485118 hasConceptScore W1967485118C2779422922 @default.
• W1967485118 hasConceptScore W1967485118C2780648677 @default.
• W1967485118 hasConceptScore W1967485118C2780852908 @default.
• W1967485118 hasConceptScore W1967485118C2780939551 @default.
• W1967485118 hasConceptScore W1967485118C42219234 @default.
• W1967485118 hasConceptScore W1967485118C513476851 @default.
• W1967485118 hasConceptScore W1967485118C55924715 @default.
• W1967485118 hasConceptScore W1967485118C71924100 @default.
• W1967485118 hasLocation W19674851181 @default.
• W1967485118 hasOpenAccess W1967485118 @default.
• W1967485118 hasPrimaryLocation W19674851181 @default.
• W1967485118 hasRelatedWork W1804730967 @default.
• W1967485118 hasRelatedWork W1916940583 @default.
• W1967485118 hasRelatedWork W1973714575 @default.
• W1967485118 hasRelatedWork W1999685173 @default.
• W1967485118 hasRelatedWork W2002957589 @default.
• W1967485118 hasRelatedWork W2037852957 @default.
• W1967485118 hasRelatedWork W2039141501 @default.
• W1967485118 hasRelatedWork W2044150564 @default.
• W1967485118 hasRelatedWork W2053590245 @default.
• W1967485118 hasRelatedWork W2055844507 @default.
• W1967485118 hasRelatedWork W2072326775 @default.
• W1967485118 hasRelatedWork W2080499383 @default.

• next