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• W1967503156 abstract "Substantial advances in our understanding of lentivirus lifecycles and their various constituent proteins have permitted the bioengineering of lentiviral vectors now considered safe enough for clinical trials for both lethal and non-lethal diseases. They possess distinct properties that make them particularly suitable for gene delivery in ophthalmic diseases, including high expression, consistent targeting of various post-mitotic ocular cells in vivo and a paucity of associated intraocular inflammation, all contributing to their ability to mediate efficient and stable intraocular gene transfer. In this review, the intraocular tropisms and therapeutic applications of both primate and non-primate lentiviral vectors, and how the unique features of the eye influence these, are discussed. The feasibility of therapeutic targeting using these vectors in animal models of both anterior and posterior ophthalmic disorders has been established, and has, in combination with substantial progress in enhancing lentiviral vector bio-safety over the past two decades, paved the way for the first human ophthalmic clinical trials using lentivirus-based gene transfer vectors." @default.
• W1967503156 created "2016-06-24" @default.
• W1967503156 creator A5033644015 @default.
• W1967503156 creator A5073699632 @default.
• W1967503156 date "2011-11-03" @default.
• W1967503156 modified "2023-09-25" @default.
• W1967503156 title "Ocular gene delivery using lentiviral vectors" @default.
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• W1967503156 cites W1972106091 @default.
• W1967503156 cites W1972583115 @default.
• W1967503156 cites W1974147843 @default.
• W1967503156 cites W1975477980 @default.
• W1967503156 cites W1976244438 @default.
• W1967503156 cites W1976599692 @default.
• W1967503156 cites W1985095994 @default.
• W1967503156 cites W1985997817 @default.
• W1967503156 cites W1986214576 @default.
• W1967503156 cites W1986668568 @default.
• W1967503156 cites W1988929331 @default.
• W1967503156 cites W1989208666 @default.
• W1967503156 cites W1989832479 @default.
• W1967503156 cites W1996955664 @default.
• W1967503156 cites W2000000541 @default.
• W1967503156 cites W2000500260 @default.
• W1967503156 cites W2003545017 @default.
• W1967503156 cites W2004529315 @default.
• W1967503156 cites W2006765654 @default.
• W1967503156 cites W2008512248 @default.
• W1967503156 cites W2009624205 @default.
• W1967503156 cites W2010303814 @default.
• W1967503156 cites W2010416043 @default.
• W1967503156 cites W2016450624 @default.
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• W1967503156 cites W2027296526 @default.
• W1967503156 cites W2031696679 @default.
• W1967503156 cites W2033627909 @default.
• W1967503156 cites W2034861882 @default.
• W1967503156 cites W2036473412 @default.
• W1967503156 cites W2041174990 @default.
• W1967503156 cites W2046156611 @default.
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• W1967503156 cites W2053474800 @default.
• W1967503156 cites W2053587516 @default.
• W1967503156 cites W2060019963 @default.
• W1967503156 cites W2065872564 @default.
• W1967503156 cites W2067300362 @default.
• W1967503156 cites W2068418960 @default.
• W1967503156 cites W2072815621 @default.
• W1967503156 cites W2074155420 @default.
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• W1967503156 doi "https://doi.org/10.1038/gt.2011.153" @default.
• W1967503156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22052240" @default.
• W1967503156 hasPublicationYear "2011" @default.
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