FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967541372> ?p ?o ?g. }

• W1967541372 endingPage "484" @default.
• W1967541372 startingPage "477" @default.
• W1967541372 abstract "Nucleophosmin (NPM, B23, numatrin, NO38) is an abundant nucleolar phosphoprotein involved in multiple cellular functions. Previous evidence indicates that high-level expression of NPM causes uncontrolled cell growth and suggests that NPM may have oncogenic potential. In this study, we examined NPM expression in 103 paired cases of hepatocellular carcinoma (HCC), 12 cases of hepatic focal nodular hyperplasia, 17 cases of liver tissue adjacent to a hepatic haemangioma, and series of array tissues from normal human organs and malignancies using a monoclonal antibody against NPM and reverse transcription-PCR techniques, Western blot analysis, immunohistochemistry, and immunocytofluorescence. Our data indicated that NPM expression was significantly higher in HCC than in the non-malignant hepatocytes (P<0.001). Nucleophosmin was weakly expressed in hepatocytes from a 5-month-old embryo and in stationary hepatocytes of healthy adults. Moreover, enhanced expression of NPM in HCC correlated with the level of PCNA (R(2)=0.5639) and with the clinical prognostic parameters such as serum alpha fetal protein level, tumour pathological grading, and liver cirrhosis (P<0.05). Our results suggest that NPM may play an important role in the progression of tumorigenesis and that NPM may serve as a potential marker for HCC." @default.
• W1967541372 created "2016-06-24" @default.
• W1967541372 creator A5006150283 @default.
• W1967541372 creator A5007877222 @default.
• W1967541372 creator A5024868599 @default.
• W1967541372 creator A5042144598 @default.
• W1967541372 creator A5048354952 @default.
• W1967541372 creator A5054997017 @default.
• W1967541372 creator A5060592435 @default.
• W1967541372 creator A5091452054 @default.
• W1967541372 date "2007-01-23" @default.
• W1967541372 modified "2023-10-07" @default.
• W1967541372 title "Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters" @default.
• W1967541372 cites W1525497365 @default.
• W1967541372 cites W1526436403 @default.
• W1967541372 cites W1554666790 @default.
• W1967541372 cites W1965912619 @default.
• W1967541372 cites W1974562538 @default.
• W1967541372 cites W1975967265 @default.
• W1967541372 cites W1979825473 @default.
• W1967541372 cites W1984829161 @default.
• W1967541372 cites W1984857402 @default.
• W1967541372 cites W1990225407 @default.
• W1967541372 cites W1990555927 @default.
• W1967541372 cites W1993513613 @default.
• W1967541372 cites W1993719557 @default.
• W1967541372 cites W2000362412 @default.
• W1967541372 cites W2001866617 @default.
• W1967541372 cites W2005041212 @default.
• W1967541372 cites W2009614003 @default.
• W1967541372 cites W2018374250 @default.
• W1967541372 cites W2019845267 @default.
• W1967541372 cites W2027731183 @default.
• W1967541372 cites W2030142625 @default.
• W1967541372 cites W2032054503 @default.
• W1967541372 cites W2037257739 @default.
• W1967541372 cites W2043895477 @default.
• W1967541372 cites W2045334190 @default.
• W1967541372 cites W2068311105 @default.
• W1967541372 cites W2078448904 @default.
• W1967541372 cites W2082496903 @default.
• W1967541372 cites W2082627145 @default.
• W1967541372 cites W2088271013 @default.
• W1967541372 cites W2090293099 @default.
• W1967541372 cites W2092837591 @default.
• W1967541372 cites W2097080348 @default.
• W1967541372 cites W2099322971 @default.
• W1967541372 cites W2115920391 @default.
• W1967541372 cites W2117812450 @default.
• W1967541372 cites W2129440779 @default.
• W1967541372 cites W2143104204 @default.
• W1967541372 cites W2167297380 @default.
• W1967541372 cites W2170515966 @default.
• W1967541372 cites W2313156944 @default.
• W1967541372 cites W2324129489 @default.
• W1967541372 cites W2350295463 @default.
• W1967541372 cites W2410547037 @default.
• W1967541372 cites W36613289 @default.
• W1967541372 cites W4239780822 @default.
• W1967541372 cites W4361741428 @default.
• W1967541372 doi "https://doi.org/10.1038/sj.bjc.6603574" @default.
• W1967541372 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2360035" @default.
• W1967541372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17245342" @default.
• W1967541372 hasPublicationYear "2007" @default.
• W1967541372 type Work @default.
• W1967541372 sameAs 1967541372 @default.
• W1967541372 citedByCount "75" @default.
• W1967541372 countsByYear W19675413722012 @default.
• W1967541372 countsByYear W19675413722013 @default.
• W1967541372 countsByYear W19675413722014 @default.
• W1967541372 countsByYear W19675413722015 @default.
• W1967541372 countsByYear W19675413722016 @default.
• W1967541372 countsByYear W19675413722017 @default.
• W1967541372 countsByYear W19675413722018 @default.
• W1967541372 countsByYear W19675413722019 @default.
• W1967541372 countsByYear W19675413722020 @default.
• W1967541372 countsByYear W19675413722021 @default.
• W1967541372 countsByYear W19675413722022 @default.
• W1967541372 countsByYear W19675413722023 @default.
• W1967541372 crossrefType "journal-article" @default.
• W1967541372 hasAuthorship W1967541372A5006150283 @default.
• W1967541372 hasAuthorship W1967541372A5007877222 @default.
• W1967541372 hasAuthorship W1967541372A5024868599 @default.
• W1967541372 hasAuthorship W1967541372A5042144598 @default.
• W1967541372 hasAuthorship W1967541372A5048354952 @default.
• W1967541372 hasAuthorship W1967541372A5054997017 @default.
• W1967541372 hasAuthorship W1967541372A5060592435 @default.
• W1967541372 hasAuthorship W1967541372A5091452054 @default.
• W1967541372 hasBestOaLocation W19675413721 @default.
• W1967541372 hasConcept C121608353 @default.
• W1967541372 hasConcept C126322002 @default.
• W1967541372 hasConcept C142724271 @default.
• W1967541372 hasConcept C18903297 @default.
• W1967541372 hasConcept C204232928 @default.
• W1967541372 hasConcept C2777286243 @default.
• W1967541372 hasConcept C2778019345 @default.
• W1967541372 hasConcept C2778729363 @default.
• W1967541372 hasConcept C2908722627 @default.

• next