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• W1967548601 abstract "SummaryIn 6 patients suffering from ataxia telangiectasia morphological evaluation of lymphoblastic transformation was performed; in one of these cases it was repeated four times. In 3 cases the incorporation of 3H-thymidine was measured to examine the degree of the lymphoblastic transformation. Both methods revealed decreased lymphoblastic transformation, though with the last method the decrease was much greater. No correlation was found between the degree of decreased blastic transformation, the infections and the plasma IgA level. Delayed-type skin reactions were subnormal in varying degrees. Increased frequency of chromosome breakage was observed in 1 case–who developed malignancy and died– but no chromosomal aberrations were found in the three other cytogenetically examined patients." @default.
• W1967548601 created "2016-06-24" @default.
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• W1967548601 date "1971-01-01" @default.
• W1967548601 modified "2023-10-16" @default.
• W1967548601 title "LYMPHOBLASTIC TRANSFORMATION, CHROMOSOME PATTERN AND DELAYED-TYPE SKIN REACTION IN ATAXIA TELANGIECTASIA" @default.
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• W1967548601 doi "https://doi.org/10.1111/j.1651-2227.1971.tb06619.x" @default.
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