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• W1967557244 abstract "The objective of this study was to assess the cytotoxicity of EndoSeal, a novel mineral trioxide aggregate-based root canal sealer in comparison with two commonly used sealers, AH Plus and Sealapex. For cytotoxicity assay, MG-63 cells and human gingival fibroblasts were incubated in culture medium containing eluates of each sealer at 1, 3, and 7 days. Cell metabolism was evaluated by the WST-1 assay. For cell adhesion assay, disc specimens were fabricated from EndoSeal and AH Plus. MG-63 cells and human gingival fibroblasts were seeded on the discs, and after 1 day and 7 days of incubation, cell morphology and cell adhesion were examined by SEM. The order of cytotoxicity of root canal sealers was as follows: EndoSeal < AH Plus < Sealapex. Both types of cells seeded on the EndoSeal specimens were much larger, flat with rough margins compared to those on the AH Plus specimens. These results suggest that EndoSeal has a satisfactory cytocompatibility." @default.
• W1967557244 created "2016-06-24" @default.
• W1967557244 creator A5055824351 @default.
• W1967557244 creator A5062170863 @default.
• W1967557244 date "2014-01-01" @default.
• W1967557244 modified "2023-10-10" @default.
• W1967557244 title "Cytotoxicity of a novel mineral trioxide aggregated-based root canal sealer" @default.
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• W1967557244 doi "https://doi.org/10.4012/dmj.2013-171" @default.
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• W1967557244 hasPublicationYear "2014" @default.
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