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• W1967576676 abstract "Background and Objectives The recurrence of hepatocellular carcinoma (HCC) after percutaneous ablation is poorly evaluated. Methods Thirty-six cases of recurrence after percutaneous ablation (PA) (Group 1) are compared to those after surgery, treated with re-resection (26 patients, Group 2) and PA (31 patients, Group 3). Results Recurrence was usually local after PA and distant after resection. Compared to Groups 2 and 3, local recurrences after PA were larger (4.2 vs. 2.3 cm) and more often invasive (43% vs. 10%). No different clinical/pathological aspects were noted in distant recurrences among the groups. After treatment the survival rate (1, 2, 3 and 5 years) was no different between the groups; in an intention-to-treat analysis of survival for local recurrences, survival was significantly lower in Group 1 (78%, 78%, 67% and 28%) than in Groups 2 and 3 (100%, 88%, 75% and 45%) (P < 0.05). Conclusions PA and surgery can be sequentially employed for HCC. The type of primary treatment does not influence the features of distant liver recurrence, while local recurrence after PA often requires more extensive liver resection. J. Surg. Oncol. 2009;100:580–584. © 2009 Wiley-Liss, Inc." @default.
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• W1967576676 date "2009-12-01" @default.
• W1967576676 modified "2023-10-16" @default.
• W1967576676 title "Sequential multidisciplinary treatment of hepatocellular carcinoma: The role of surgery as rescue therapy for failure of percutaneous ablation therapies" @default.
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• W1967576676 doi "https://doi.org/10.1002/jso.21375" @default.
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