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- W1967597082 abstract "Pharmacodynamics and toxicodynamics are the study of the biochemical and physiological effects of therapeutic agents and toxicants and their mechanisms of action. MALDI-MS imaging offers great potential for the study of pharmaco/toxicodynamic responses in tissue owing is its ability to study multiple biomarkers simultaneously in a label-free manner. Here, existing examples of such studies examining anticancer drugs and topically applied treatments are described. Examination of the literature shows that the use of MS imaging in pharmaco/toxicodynamic studies is in fact quite low. The reasons for this are discussed and potential developments in the methodology that might lead to its further use are described." @default.
- W1967597082 created "2016-06-24" @default.
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- W1967597082 date "2015-01-01" @default.
- W1967597082 modified "2023-10-02" @default.
- W1967597082 title "MALDI-MS imaging for the study of tissue pharmacodynamics and toxicodynamics" @default.
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- W1967597082 doi "https://doi.org/10.4155/bio.14.280" @default.
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