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- W1967601023 abstract "There is evidence that habitual consumption of green tea by Japanese men is correlated with a reduction in cancers, including prostate; soybean isoflavones are also associated with increased protection. The present study compared the anti-proliferative effect of black tea (Camellia sinensis) polyphenol, thearubigin (TR), alone or combined with the isoflavone genistein, on human prostate (PC-3) carcinoma cells. TR administered alone did not result in any alteration of cell growth. When combined with genistein, however, TR significantly inhibited cell growth and induced a G2/M phase cell cycle arrest in a dose dependent manner. These findings indicate the potential use of combined phytochemicals to provide protection against prostate cancer." @default.
- W1967601023 created "2016-06-24" @default.
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- W1967601023 date "2000-04-01" @default.
- W1967601023 modified "2023-10-15" @default.
- W1967601023 title "Synergistic effects of thearubigin and genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest" @default.
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- W1967601023 doi "https://doi.org/10.1016/s0304-3835(99)00423-1" @default.
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