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- W1967602011 abstract "Isolated HeLa plasma membrane (PM) preparations and extracts containing either cell-surface proteins or lipids were examined for inhibition of adherence of radiolabeled Chlamydia trachomatis serovar E elementary bodies to glutaraldehyde-fixed HeLa monolayers. A dose-dependent adherence-inhibitory activity could be demonstrated with the PM. A urea extract as well as lipids from HeLa cells also inhibited chlamydial cytadherence. The inhibitory activity of the PM was trypsin-sensitive. It was absent when the urea extract was prepared from trypsin-treated HeLa cells. The urea extract was subjected to electrophoresis and protein blotting using a native gel system. Probing with radiolabeled chlamydial cytadhesin showed a single protein present in the urea extract that could represent a HeLa cell protein receptor for the chlamydiae." @default.
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- W1967602011 date "1992-03-01" @default.
- W1967602011 modified "2023-10-18" @default.
- W1967602011 title "Surface components of HeLa cells that inhibit cytadherence of Chlamydia trachomatis" @default.
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- W1967602011 doi "https://doi.org/10.1016/0378-1097(92)90680-m" @default.
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