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• W1967701207 abstract "The exposure of human lymphoid leukemia Molt 4B cells to pheophorbide a (PPB a), a moiety of chlorophyll a, led both to growth inhibition and induction of programmed cell death (apoptosis). The growth inhibition by PPB a was much stronger than that by chlorophyll a. Morphological change showing apoptotic bodies was observed in the Molt 4B cells treated with PPB a. The fragmentation by PPB a of DNA to oligonucleosomal-sized fragments, that are characteristics of apoptosis, was observed to be concentration- and time-dependent. These findings suggest that growth inhibition by PPB a of Molt 4B cells results from the induction of apoptosis and that PPB a, moiety of chlorophyll a, is essential for exertion of antitumor and apoptosis-inducing activity in these cells." @default.
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• W1967701207 date "2000-09-01" @default.
• W1967701207 modified "2023-09-27" @default.
• W1967701207 title "Pheophorbide a, a moiety of chlorophyll a, induces apoptosis in human lymphoid leukemia molt 4B cells." @default.
• W1967701207 doi "https://doi.org/10.3892/ijmm.6.3.277" @default.
• W1967701207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10934289" @default.
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