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• W1967720787 endingPage "535" @default.
• W1967720787 startingPage "527" @default.
• W1967720787 abstract "Microglia are the intrinsic immune cells of the brain and express chemokine and cytokine receptors that interact with the peripheral immune cells. Recent studies have indicated that microglia also respond to the brain's classical signalling substances, the neurotransmitters. Here, we review the evidence for the expression of neurotransmitter receptors on microglia and the consequences of this receptor activation for microglial behaviour. It is evident that neurotransmitters instruct microglia to perform distinct types of responses, such as triggering an inflammatory cascade or acquiring a neuroprotective phenotype. Understanding how microglia respond to different neurotransmitters will thus have important implications for controlling the reactivity of these cells in acute injury, as well as for treating chronic neurodegenerative diseases." @default.
• W1967720787 created "2016-06-24" @default.
• W1967720787 creator A5068969195 @default.
• W1967720787 creator A5086549313 @default.
• W1967720787 date "2007-10-01" @default.
• W1967720787 modified "2023-10-03" @default.
• W1967720787 title "Neurotransmitter receptors on microglia" @default.
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• W1967720787 doi "https://doi.org/10.1016/j.tins.2007.07.007" @default.
• W1967720787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17904651" @default.

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