Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967760412> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1967760412 abstract "Chlamydiae are prokaryotic, gram negative, intracellular parasites, causing a number of human diseases with serious sequelae. The exact mechanism of chlamydial attachment and entry into the host cell is still unclear. Chlamydia trachomatis, SA2F (L2) was tested for the activity of glycosidases. Glycosidases are involved in the synthesis and breakdown of cell-wall polysaccharides, and have a pivotal role in attachment to the surface of host cells as well as in the invasion process of other infective agents. For these reasons, glycosidases are likely to provide important information regarding the general behaviour of this bacterium. Ten different glycosides bound to p-nitrophenol (pNP) substrate were tested. Assays were performed on lysed and unlysed chlamydial extracts. Our results provided strong evidence for the existence of glycosidase activity in C. trachomatis, strain SA2F peaking at pH 5.0 and pH 7.5-8.0 There was a high enzymatic activity against p-NPa mannopyranoside and p-NP b-N acetylglucosamine with a recovery of 88% suggesting that the enzymes were present on the bacterial surface. Activity against these sugars, which form part of either the extracellular filler or in endoplasmic reticulum may suggest of a possible mechanism of cellular invasion. Keywords: Chlamydia trachomatis, glycosidases, sexually transmitted infection, p-NPa mannopyranoside, p-NP b-N acetylglucosamine. Internet Journal of Medical Update Vol. 1 (1) 2006: pp. 24-31" @default.
- W1967760412 created "2016-06-24" @default.
- W1967760412 creator A5009252193 @default.
- W1967760412 creator A5071679095 @default.
- W1967760412 creator A5082993642 @default.
- W1967760412 date "2007-11-01" @default.
- W1967760412 modified "2023-09-24" @default.
- W1967760412 title "Analysis of glycosidases activity in <i>Chlamydia trachomatis</i> L2 serotype" @default.
- W1967760412 cites W1496882149 @default.
- W1967760412 cites W155808164 @default.
- W1967760412 cites W1912648131 @default.
- W1967760412 cites W1976220634 @default.
- W1967760412 cites W2024941185 @default.
- W1967760412 cites W2077601019 @default.
- W1967760412 cites W2111413785 @default.
- W1967760412 cites W2115020053 @default.
- W1967760412 cites W2115780677 @default.
- W1967760412 cites W2120845451 @default.
- W1967760412 cites W2127136379 @default.
- W1967760412 cites W2136764190 @default.
- W1967760412 cites W2139410878 @default.
- W1967760412 cites W2144075478 @default.
- W1967760412 cites W2338831354 @default.
- W1967760412 cites W2462178453 @default.
- W1967760412 cites W2579462678 @default.
- W1967760412 cites W620629334 @default.
- W1967760412 cites W63460368 @default.
- W1967760412 doi "https://doi.org/10.4314/ijmu.v1i1.39832" @default.
- W1967760412 hasPublicationYear "2007" @default.
- W1967760412 type Work @default.
- W1967760412 sameAs 1967760412 @default.
- W1967760412 citedByCount "0" @default.
- W1967760412 crossrefType "journal-article" @default.
- W1967760412 hasAuthorship W1967760412A5009252193 @default.
- W1967760412 hasAuthorship W1967760412A5071679095 @default.
- W1967760412 hasAuthorship W1967760412A5082993642 @default.
- W1967760412 hasBestOaLocation W19677604122 @default.
- W1967760412 hasConcept C100817775 @default.
- W1967760412 hasConcept C10389963 @default.
- W1967760412 hasConcept C125235067 @default.
- W1967760412 hasConcept C1491633281 @default.
- W1967760412 hasConcept C159047783 @default.
- W1967760412 hasConcept C181199279 @default.
- W1967760412 hasConcept C185592680 @default.
- W1967760412 hasConcept C196032511 @default.
- W1967760412 hasConcept C22222904 @default.
- W1967760412 hasConcept C2777391075 @default.
- W1967760412 hasConcept C2779204014 @default.
- W1967760412 hasConcept C28406088 @default.
- W1967760412 hasConcept C523546767 @default.
- W1967760412 hasConcept C54355233 @default.
- W1967760412 hasConcept C55493867 @default.
- W1967760412 hasConcept C57409179 @default.
- W1967760412 hasConcept C79879829 @default.
- W1967760412 hasConcept C86803240 @default.
- W1967760412 hasConcept C89423630 @default.
- W1967760412 hasConceptScore W1967760412C100817775 @default.
- W1967760412 hasConceptScore W1967760412C10389963 @default.
- W1967760412 hasConceptScore W1967760412C125235067 @default.
- W1967760412 hasConceptScore W1967760412C1491633281 @default.
- W1967760412 hasConceptScore W1967760412C159047783 @default.
- W1967760412 hasConceptScore W1967760412C181199279 @default.
- W1967760412 hasConceptScore W1967760412C185592680 @default.
- W1967760412 hasConceptScore W1967760412C196032511 @default.
- W1967760412 hasConceptScore W1967760412C22222904 @default.
- W1967760412 hasConceptScore W1967760412C2777391075 @default.
- W1967760412 hasConceptScore W1967760412C2779204014 @default.
- W1967760412 hasConceptScore W1967760412C28406088 @default.
- W1967760412 hasConceptScore W1967760412C523546767 @default.
- W1967760412 hasConceptScore W1967760412C54355233 @default.
- W1967760412 hasConceptScore W1967760412C55493867 @default.
- W1967760412 hasConceptScore W1967760412C57409179 @default.
- W1967760412 hasConceptScore W1967760412C79879829 @default.
- W1967760412 hasConceptScore W1967760412C86803240 @default.
- W1967760412 hasConceptScore W1967760412C89423630 @default.
- W1967760412 hasIssue "1" @default.
- W1967760412 hasLocation W19677604121 @default.
- W1967760412 hasLocation W19677604122 @default.
- W1967760412 hasOpenAccess W1967760412 @default.
- W1967760412 hasPrimaryLocation W19677604121 @default.
- W1967760412 hasRelatedWork W1147280289 @default.
- W1967760412 hasRelatedWork W1571349503 @default.
- W1967760412 hasRelatedWork W2013198018 @default.
- W1967760412 hasRelatedWork W2065393786 @default.
- W1967760412 hasRelatedWork W2104304617 @default.
- W1967760412 hasRelatedWork W2149828168 @default.
- W1967760412 hasRelatedWork W2401629385 @default.
- W1967760412 hasRelatedWork W2482787946 @default.
- W1967760412 hasRelatedWork W3022214722 @default.
- W1967760412 hasRelatedWork W7994175 @default.
- W1967760412 hasVolume "1" @default.
- W1967760412 isParatext "false" @default.
- W1967760412 isRetracted "false" @default.
- W1967760412 magId "1967760412" @default.
- W1967760412 workType "article" @default.