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• W1967803471 abstract "In this review, studies are described indicating that the increase in pulsatile release of gonadotropin releasing hormone that signals the initiation of puberty requires both changes in transsynaptic communication and the activation of glia-to-neuron signaling pathways. The major players in the transsynaptic control of puberty are neurons that utilize excitatory and inhibitory amino acids as transmitters. Glial cells employ a combination of trophic factors and small cell-cell signaling molecules to regulate neuronal function and thus promote sexual development. A neuron-to-glia signaling pathway mediated by excitatory amino acids serves to coordinate the simultaneous activation of transsynaptic and glia-to-neuron communication required for the advent of sexual maturity." @default.
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• W1967803471 date "2003-01-01" @default.
• W1967803471 modified "2023-10-16" @default.
• W1967803471 title "The Neurobiology of Female Puberty" @default.
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• W1967803471 doi "https://doi.org/10.1159/000074495" @default.
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