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- W1967803774 abstract "The effect of therapeutic hypothermia on sedative drug clearance and neurological prognostication is unknown. Hypothermia has been shown to affect clearance of drugs metabolised by the cytochrome p450 system (fentanyl, midazolam and muscle relaxants) [1]. We undertook a retrospective study to ascertain whether the use of remifentanil sedation was associated with reduced duration of ICU stay, ventilation, mortality or neurological outcome compared with fentanyl in patients undergoing therapeutic hypothermia." @default.
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- W1967803774 date "2009-01-01" @default.
- W1967803774 modified "2023-09-26" @default.
- W1967803774 title "Does choice of sedative agent affect duration of ICU stay, mortality or neurological outcome in patients undergoing therapeutic hypothermia?" @default.
- W1967803774 cites W1995298539 @default.
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- W1967803774 doi "https://doi.org/10.1186/cc7564" @default.
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