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• W1967817078 abstract "Optimal treatment of prosthetic valve endocarditis due to Brucella melitensis is unknown. The presence of ring abscess makes extensive surgical débridement and valve replacement essential steps of management. Antimicrobial therapy with tetracycline hydrochloride plus streptomycin sulfate or sulfamethoxazole and trimethoprim can achieve the sterilization of infected cardiac tissue. Late bland periprosthetic leaks occur frequently. Reoperation can be safely performed after a period of antimicrobial therapy. Prolonged treatment with doxycycline hyclate seems advisable." @default.
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• W1967817078 date "1987-06-01" @default.
• W1967817078 modified "2023-10-03" @default.
• W1967817078 title "Prosthetic Valve Endocarditis Caused by Brucella melitensis" @default.
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• W1967817078 doi "https://doi.org/10.1001/archinte.1987.00370060137022" @default.
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