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- W1967828500 abstract "All-trans-retinoic acid (ATRA) has a dramatic antitumor effect in patients with acute promyelocytic leukemia (APL). It is hepatically metabolized by cytochrome P-450, and there are known toxicities associated with high levels of this drug. The effects of ATRA can be potentiated by inhibition of cytochrome P-450, which is known to occur with certain drugs. We report a case of a patient with ATRA toxicity thought to be secondary to interaction with fluconazole." @default.
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- W1967828500 date "2003-05-01" @default.
- W1967828500 modified "2023-09-27" @default.
- W1967828500 title "Interaction of All-Trans-Retinoic Acid With Fluconazole in Acute Promyelocytic Leukemia" @default.
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- W1967828500 doi "https://doi.org/10.1097/00043426-200305000-00010" @default.
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