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- W1967882647 abstract "An extensive literature has accumulated<sup>1</sup>reporting the toxic effects of sulfanilamide on the blood forming organs. These reactions consist of acute hemolytic anemia with leukocytosis, occasionally a leukemoid blood picture,<sup>2</sup>severe leukopenia with granulocytopenia and thrombopenia with hemorrhagic phenomena. Such deviations may occur singly or in combination. The outcome occasionally has been fatal.<sup>3</sup>The cases reported up to the present time usually have presented initially a normal hemoglobin and red cell count or slightly diminished values. A careful search of the literature fails to disclose any referenceto a case of polycythemia vera in which there was a toxic reaction of the blood in the course of the administration of sulfanilamide. The following is the report of a case of polycythemia vera and prostatic infection in which anemia, severe leukopenia and neutropenia developed as the result of the administration of sulfanilamide. A white man aged 61, born" @default.
- W1967882647 created "2016-06-24" @default.
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- W1967882647 date "1942-03-21" @default.
- W1967882647 modified "2023-09-26" @default.
- W1967882647 title "TOXIC EFFECT OF SULFANILAMIDE ON THE HEMOPOIETIC ORGANS IN A CASE OF POLYCYTHEMIA VERA" @default.
- W1967882647 cites W1978918676 @default.
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- W1967882647 doi "https://doi.org/10.1001/jama.1942.62830120003011b" @default.
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