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- W1967910956 abstract "Objective: Primary care physicians control patients treated with Oral Anticoagulant Therapy (OAT). The progressive aging of the population, with the increase of cardiovascular morbidity, have enlarged the number of patients that receive OAT. Despite their increased risk, we unknow the incidence of thrombotic-hemorrhagic events. We analyzed the frequentation in the emergencies service in our reference hospital, the morbidity and its association to the use of OAT. Design and Method: This is a descriptive study of patients receiving OAT for 6 months during 2008. The variables were obtained after the approval of the Ethical Committe, adjusted to the Organic Law of Personal Data Protection. We calculated the number of patients with HyTex®. We sought an accuracy of 5% in the estimation of a proportion (normal asymptotic confidence interval with correction for finite population, 95% two-sided). Expected proportion of 50% and a loss of 10%, the final size was 275 patients. We searched for a relation of hospitalary attendance and duration of admission with OAT. The quantitative variables were mean and standard deviation; frequency as qualitative (95% confidence intervals). We analyzed patient subgroups. All statistical tests were two-tailed. We regarded as significant p < 0,05. The software used was SPSS 15.0. Results: 53,6% of the patients were attended in the emergency service. We assessed 371 admissions. The mean duration was 3,26 days, (global stay of 1209 days). The most frequent diagnoses: heart failure, respiratory tract infection and atrial fibrillation. In terms of the International Classification of Diseases, cardiac pathology provokes 32,9% of the admissions. In 62 cases, it was appreciated a relation of the cause of the admission with the use of OAT, and hemorrhagic events, where the most frequent were nasal, oral, subconjunctival and bladder hemorrhage. Other included: gastrointestinal bleeding, cerebrovascular and heart events. One person died of a cerebral hemorrhage. Conclusions: Our patients asked for attendance for causes normally non-related with the use of OAT. The detected pathology matches the expected adverse effects, involving a scarce mortality." @default.
- W1967910956 created "2016-06-24" @default.
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- W1967910956 date "2010-06-01" @default.
- W1967910956 modified "2023-09-26" @default.
- W1967910956 title "HOSPITALARY MORBIDITY ASSOCIATED TO THE USE OF ORAL ANTICOAGULANTS: PP.33.328" @default.
- W1967910956 doi "https://doi.org/10.1097/01.hjh.0000379866.44792.2f" @default.
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