Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967911217> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1967911217 endingPage "1089" @default.
- W1967911217 startingPage "1081" @default.
- W1967911217 abstract "Only 53% and 63% of studies and clinical trials results presented at congresses are published. Company-sponsored trial results are being posted on publicly accessible Web sites. We analyzed the public availability (publication or posting on a Web site) rate, time to publication, and factors predicting public availability of results of studies sponsored by a pharmaceutical company. This was a retrospective cohort study analyzing all studies conducted by GlaxoSmithKline in Spain between 2001 and 2006. Initiation and completion were defined as first participant/first visit and last participant/last visit (or their equivalents). Papers published up to 31 March 2009 were considered. Logistic regression models were used to identify factors predicting public availability of results. The cohort comprised 143 studies (94 clinical trials; of these, 87 were included in international products clinical development plans). Public availability rate was 80% (114/143) for all studies and 78% (73/94) for clinical trials; publication rates were 68% and 61%, respectively. The median time to publication for all studies and trials was 27.3 and 28.4 months, respectively. Study associated to a cancelled project was the only significant factor associated with lower publication rate for all studies [odds ratio (OR) 0.069; 95% confidence interval (CI) 0.02–024; p < 0.001) and trials (OR 0.075; 95% CI 0.016–0.343; p = 0.001) and a lower public availability rate (OR 0.052; 95% CI 0.007–0.382; p = 0.004) for trial results. Therapy area, sample size, positive trial results, duration of experimental phase, and being a clinical trial did not predict publication or public availability. Eighty percent of studies included in this analysis are publicly available. Web site posting increases public availability rate of clinical trial results from 61% to 78%. Cancellation of projects is the single factor negatively influencing publication and public availability rates." @default.
- W1967911217 created "2016-06-24" @default.
- W1967911217 creator A5019738713 @default.
- W1967911217 creator A5020420490 @default.
- W1967911217 creator A5031512398 @default.
- W1967911217 creator A5037096484 @default.
- W1967911217 creator A5091880543 @default.
- W1967911217 date "2010-09-16" @default.
- W1967911217 modified "2023-10-18" @default.
- W1967911217 title "Are results from pharmaceutical-company-sponsored studies available to the public?" @default.
- W1967911217 cites W1592653824 @default.
- W1967911217 cites W1603293637 @default.
- W1967911217 cites W1966957373 @default.
- W1967911217 cites W1970223153 @default.
- W1967911217 cites W1971948511 @default.
- W1967911217 cites W1973679249 @default.
- W1967911217 cites W1976366538 @default.
- W1967911217 cites W1986029333 @default.
- W1967911217 cites W1988851494 @default.
- W1967911217 cites W1990624992 @default.
- W1967911217 cites W1993437256 @default.
- W1967911217 cites W2025348020 @default.
- W1967911217 cites W2027652926 @default.
- W1967911217 cites W2028540474 @default.
- W1967911217 cites W2048056673 @default.
- W1967911217 cites W2058534885 @default.
- W1967911217 cites W2064223985 @default.
- W1967911217 cites W2065347109 @default.
- W1967911217 cites W2066896354 @default.
- W1967911217 cites W2075286521 @default.
- W1967911217 cites W2091959199 @default.
- W1967911217 cites W2103718021 @default.
- W1967911217 cites W2105662053 @default.
- W1967911217 cites W2108513996 @default.
- W1967911217 cites W2112339576 @default.
- W1967911217 cites W2124626725 @default.
- W1967911217 cites W2128188088 @default.
- W1967911217 cites W2145261968 @default.
- W1967911217 cites W2149994900 @default.
- W1967911217 cites W2153624905 @default.
- W1967911217 cites W4248288478 @default.
- W1967911217 cites W4256484569 @default.
- W1967911217 doi "https://doi.org/10.1007/s00228-010-0898-y" @default.
- W1967911217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20844869" @default.
- W1967911217 hasPublicationYear "2010" @default.
- W1967911217 type Work @default.
- W1967911217 sameAs 1967911217 @default.
- W1967911217 citedByCount "5" @default.
- W1967911217 countsByYear W19679112172012 @default.
- W1967911217 countsByYear W19679112172013 @default.
- W1967911217 countsByYear W19679112172016 @default.
- W1967911217 crossrefType "journal-article" @default.
- W1967911217 hasAuthorship W1967911217A5019738713 @default.
- W1967911217 hasAuthorship W1967911217A5020420490 @default.
- W1967911217 hasAuthorship W1967911217A5031512398 @default.
- W1967911217 hasAuthorship W1967911217A5037096484 @default.
- W1967911217 hasAuthorship W1967911217A5091880543 @default.
- W1967911217 hasBestOaLocation W19679112172 @default.
- W1967911217 hasConcept C126322002 @default.
- W1967911217 hasConcept C151956035 @default.
- W1967911217 hasConcept C156957248 @default.
- W1967911217 hasConcept C201903717 @default.
- W1967911217 hasConcept C44249647 @default.
- W1967911217 hasConcept C512399662 @default.
- W1967911217 hasConcept C535046627 @default.
- W1967911217 hasConcept C71924100 @default.
- W1967911217 hasConceptScore W1967911217C126322002 @default.
- W1967911217 hasConceptScore W1967911217C151956035 @default.
- W1967911217 hasConceptScore W1967911217C156957248 @default.
- W1967911217 hasConceptScore W1967911217C201903717 @default.
- W1967911217 hasConceptScore W1967911217C44249647 @default.
- W1967911217 hasConceptScore W1967911217C512399662 @default.
- W1967911217 hasConceptScore W1967911217C535046627 @default.
- W1967911217 hasConceptScore W1967911217C71924100 @default.
- W1967911217 hasIssue "11" @default.
- W1967911217 hasLocation W19679112171 @default.
- W1967911217 hasLocation W19679112172 @default.
- W1967911217 hasLocation W19679112173 @default.
- W1967911217 hasLocation W19679112174 @default.
- W1967911217 hasOpenAccess W1967911217 @default.
- W1967911217 hasPrimaryLocation W19679112171 @default.
- W1967911217 hasRelatedWork W2037611947 @default.
- W1967911217 hasRelatedWork W2138334887 @default.
- W1967911217 hasRelatedWork W2335988042 @default.
- W1967911217 hasRelatedWork W2508184277 @default.
- W1967911217 hasRelatedWork W2971695752 @default.
- W1967911217 hasRelatedWork W3010075638 @default.
- W1967911217 hasRelatedWork W3139085109 @default.
- W1967911217 hasRelatedWork W3183421467 @default.
- W1967911217 hasRelatedWork W4321201241 @default.
- W1967911217 hasRelatedWork W4322739880 @default.
- W1967911217 hasVolume "66" @default.
- W1967911217 isParatext "false" @default.
- W1967911217 isRetracted "false" @default.
- W1967911217 magId "1967911217" @default.
- W1967911217 workType "article" @default.