FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967915226> ?p ?o ?g. }

• W1967915226 endingPage "319" @default.
• W1967915226 startingPage "309" @default.
• W1967915226 abstract "Quartz has the least favored surface among many oxides for bacterial attachment and for lipid bilayer or micelle interactions. Tetrahedrally coordinated crystalline silica polymorphs are membranolytic toward liposomes, lysosomes, erythrocytes, and macrophages. Amorphous silica, the octahedral silica polymorph, (stishovite), and oxides such as Al2O3, Fe2O3, and TiO2 are less cytotoxic. Existing theories for membrane rupture that invoke interactions between oxide surfaces and cell membrane phospholipids (PLs) do not adequately explain these differences in membranolytic potential of the oxides. The author presents a crystal chemical, thermodynamic model for the initial interaction of oxide surfaces with the quaternary ammonium component of the PL's polar head group. The model includes solvation energy changes and electrostatic forces during adsorption, represented by the dielectric constant of the solid and the charge-to-radius ratio of the adsorbing solute. The nature of oxide–solute interactions compared with oxide–water, solute–water, and water–water interactions determines the membranolytic activity of the oxide, where the solute is TMA+, the quaternary ammonium moeity. Significant membrane rupture, as on quartz, requires unfavorable adsorption entropy (ΔSads,TMA+<0) to maximize disruption of normal membrane structure and requires favorable Gibbs free energy of exchange between TMA+ and the ambient Na+ ions (ΔGexc,TMA+/Na+=ΔGads,TMA+−ΔGads,Na+<0) to maximize the extent of membrane affected. For amorphous silica, ΔSads,TMA+>0, so disruption of structure is limited, even though ΔGexc,TMA+/Na+ is <0. Stishovite and other oxides have ΔSads,TMA+<0, but now ΔGexc,TMA+/Na+ is >0 at the acidic to circumneutral pHs of cellular and subcellular organelle fluids. The model predicts the correct sequence of membranolytic ability: quartz ≥ amorphous SiO2>Al2O3>Fe2O3>TiO2. The model thus explains the relatively poor adhesion of bacterial cells to quartz and the lack of quartz as a biomineral. It is proposed that one function of extracellular polymeric substances exuded by bacteria is to render mineral surfaces more hydrophilic." @default.
• W1967915226 created "2016-06-24" @default.
• W1967915226 creator A5052377969 @default.
• W1967915226 date "2002-08-01" @default.
• W1967915226 modified "2023-09-27" @default.
• W1967915226 title "Biomembrane Phospholipid–Oxide Surface Interactions: Crystal Chemical and Thermodynamic Basis" @default.
• W1967915226 cites W1512695912 @default.
• W1967915226 cites W1614400845 @default.
• W1967915226 cites W1745304036 @default.
• W1967915226 cites W1881565842 @default.
• W1967915226 cites W1964121487 @default.
• W1967915226 cites W1972806843 @default.
• W1967915226 cites W1982542597 @default.
• W1967915226 cites W1983248639 @default.
• W1967915226 cites W1983312523 @default.
• W1967915226 cites W1985166529 @default.
• W1967915226 cites W1985469984 @default.
• W1967915226 cites W1986417274 @default.
• W1967915226 cites W1986798456 @default.
• W1967915226 cites W1987482837 @default.
• W1967915226 cites W1992524194 @default.
• W1967915226 cites W1997193502 @default.
• W1967915226 cites W1998015586 @default.
• W1967915226 cites W2003012885 @default.
• W1967915226 cites W2004200788 @default.
• W1967915226 cites W2008683628 @default.
• W1967915226 cites W2013123320 @default.
• W1967915226 cites W2014057197 @default.
• W1967915226 cites W2017962683 @default.
• W1967915226 cites W2019790361 @default.
• W1967915226 cites W2022690372 @default.
• W1967915226 cites W2023151048 @default.
• W1967915226 cites W2023374869 @default.
• W1967915226 cites W2023602371 @default.
• W1967915226 cites W2032232386 @default.
• W1967915226 cites W2036963891 @default.
• W1967915226 cites W2040866285 @default.
• W1967915226 cites W2041290673 @default.
• W1967915226 cites W2044304857 @default.
• W1967915226 cites W2044339054 @default.
• W1967915226 cites W2045877572 @default.
• W1967915226 cites W2048378664 @default.
• W1967915226 cites W2048379520 @default.
• W1967915226 cites W2050276315 @default.
• W1967915226 cites W2052870554 @default.
• W1967915226 cites W2057573841 @default.
• W1967915226 cites W2063902810 @default.
• W1967915226 cites W2065506976 @default.
• W1967915226 cites W2066527077 @default.
• W1967915226 cites W2068559689 @default.
• W1967915226 cites W2070575975 @default.
• W1967915226 cites W2076703003 @default.
• W1967915226 cites W2077207863 @default.
• W1967915226 cites W2081921061 @default.
• W1967915226 cites W2083504724 @default.
• W1967915226 cites W2087041232 @default.
• W1967915226 cites W2090710586 @default.
• W1967915226 cites W2091967142 @default.
• W1967915226 cites W2092482146 @default.
• W1967915226 cites W2111031157 @default.
• W1967915226 cites W2119894260 @default.
• W1967915226 cites W2120077633 @default.
• W1967915226 cites W2135298847 @default.
• W1967915226 cites W2146197743 @default.
• W1967915226 cites W2156979726 @default.
• W1967915226 cites W2157478589 @default.
• W1967915226 cites W2160255483 @default.
• W1967915226 cites W2312557347 @default.
• W1967915226 cites W2315892471 @default.
• W1967915226 cites W2326851456 @default.
• W1967915226 cites W2328661125 @default.
• W1967915226 cites W2329211284 @default.
• W1967915226 cites W2950340970 @default.
• W1967915226 cites W4230459335 @default.
• W1967915226 doi "https://doi.org/10.1006/jcis.2002.8448" @default.
• W1967915226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16290794" @default.
• W1967915226 hasPublicationYear "2002" @default.
• W1967915226 type Work @default.
• W1967915226 sameAs 1967915226 @default.
• W1967915226 citedByCount "30" @default.
• W1967915226 countsByYear W19679152262012 @default.
• W1967915226 countsByYear W19679152262013 @default.
• W1967915226 countsByYear W19679152262014 @default.
• W1967915226 countsByYear W19679152262015 @default.
• W1967915226 countsByYear W19679152262021 @default.
• W1967915226 countsByYear W19679152262023 @default.
• W1967915226 crossrefType "journal-article" @default.
• W1967915226 hasAuthorship W1967915226A5052377969 @default.
• W1967915226 hasConcept C121332964 @default.
• W1967915226 hasConcept C127413603 @default.
• W1967915226 hasConcept C146477669 @default.
• W1967915226 hasConcept C147789679 @default.
• W1967915226 hasConcept C148093993 @default.
• W1967915226 hasConcept C150394285 @default.
• W1967915226 hasConcept C178790620 @default.
• W1967915226 hasConcept C179104552 @default.
• W1967915226 hasConcept C185592680 @default.
• W1967915226 hasConcept C2779851234 @default.

• next