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- W1967939274 abstract "The goal of the present study is to develop a classification model for use in primary care using markers which are relatively easy to determine to aid early identification of persons at risk for dementia. Data were used from the Origins of Variance in the Old-Old (OCTO-Twin) study. The baseline sample included 521 non-demented subjects aged 80 and older. Relevant predictors on dementia were collected two years prior to dementia diagnosis. Dementia diagnosis was based on DSM-III-R criteria. Data were analyzed using generalized estimating equations and Cox survival analyses. Overall, the two-year incidence of dementia was 6.9%. Reporting memory complaints was the strongest predictor of dementia. Memory complaints and a MMSE score ≤ 25 resulted in a predictive value for dementia of 28.8%. No memory complaints, drinking no alcohol and a MMSE score ≤ 24 resulted in a predictive value of 18.0%. Reporting no memory complaints, drinking alcohol, having functional limitations and a MMSE score ≤ 24 resulted in a percentage of 24.7% identified with dementia after two years of follow-up. The developed classification tree could contribute to early identification of persons at risk for dementia in primary care in a feasible and cost-effective way." @default.
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- W1967939274 date "2009-07-01" @default.
- W1967939274 modified "2023-09-26" @default.
- W1967939274 title "P3-124: Classification models for early identification of persons at risk for dementia" @default.
- W1967939274 doi "https://doi.org/10.1016/j.jalz.2009.04.1099" @default.
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