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• W1967940986 abstract "Background: Remote controlled movement of wireless capsule endoscope might improve diagnosis by allowing controlled examination of gastrointestinal pathology and is a pre-requisite for precise therapeutic intervention with capsule endoscopy. Aim: To develop a radio-controlled electrostimulation capsule (RESC) to propel and alter the direction of movement of a wireless capsule endoscope and to test it in man. Methods: A radio-controlled electrostimulation capsule measuring 11 × 33 mm was constructed. It featured paired bipolar electrodes inset at both ends of the capsule arranged to deliver sufficient current to cause circular muscular contraction in the gut to propel the capsule forwards and backwards. Small circuits inside the capsule were designed to receive commands and deliver pulses to move the capsule in the anesthetized pig and unanesthetized human gastrointestinal tract. 2 miniature batteries powered the device. Yellow, green and red LEDs indicated forwards or backwards electrostimulation and a strobe effect coincided with the electrostimulation frequency. An internal photodiode trigger was used to switch the device on and off. The RESC was attached to an identically sized wireless capsule endoscope by a short cable with the endoscope dome-window viewing the RESC. A command radio-control module allowed independent testing of the LEDs, could switch the electrostimulation from forwards to backwards and deliver single test pulses to tissue. A go button commanded forwards or backwards motion. A loop aerial over the abdomen delivered radio command signals. Real-time image analysis software was used to acquire capsule images using the Given-Imaging Pill-Cam. Results: The RESC worked well in animal and human trials. A “tongue-test” was developed to check the LED's and physical effect of the electrostimulation prior to swallowing. The RESC was used as a tug or engine to pull or push a Pill-Cam at will. The direction and effect of the electrostimulation signal was imaged in real-time using the wireless capsule endoscope. The combination double sausage capsule-tug combination proved easy to swallow by a human volunteer. The RESC was observed functioning in the esophagus, stomach and duodenum using both conventional endoscopes and the attached wireless capsule endoscope. Conclusion: An autonomous radiocontrolled robotic capsular endoscope with forwards and reverse movement function was tested successfully in the porcine and human gastrointestinal tract." @default.
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• W1967940986 date "2005-04-01" @default.
• W1967940986 modified "2023-09-27" @default.
• W1967940986 title "Radiocontrolled Movement of a Robot Endoscope in the Human Gastrointestinal Tract" @default.
• W1967940986 doi "https://doi.org/10.1016/s0016-5107(05)00660-7" @default.
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