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- W1967950496 abstract "Surgical treatment of a malignancy in the trachea may lead to a long resection that has to be reconstructed with an artificial prosthesis. However, most of the available prostheses encounter inflammatory rejection and mechanical constraint problems. To improve tracheal rehabilitation a porous titanium prosthesis was developed. The aim of this study was to test the biocompatibility of this novel material.Seventeen rats had a partial tracheal prosthesis made of porous titanium inserted in the cervical trachea. The histologic analysis of the tissue surrounding the prosthesis was performed in 11 surviving animals after a period of 15 to 41 days.Fibroblast colonization of titanium pores and a ciliary cylindrical epithelial layer developed on the endoluminal side of the prosthesis and the inflammatory reaction was minimal.The results of this short-term study validate, from surgical and histologic standpoints, the usefulness of a porous titanium tracheal prosthesis." @default.
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- W1967950496 date "2002-06-01" @default.
- W1967950496 modified "2023-09-27" @default.
- W1967950496 title "Survival analysis of rats implanted with porous titanium tracheal prosthesis" @default.
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- W1967950496 doi "https://doi.org/10.1016/s0003-4975(02)03569-5" @default.
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