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- W1967965852 abstract "Sperm are guided to the egg by a gradient of chemical attractants - a process called chemotaxis. The binding of the chemoattractant to receptors on the surface of the flagellum triggers a cascade of signaling events that eventually lead to an influx of Ca(2+) ions. Based on these Ca(2+) surges, which control the waveform of the flagellar beat, sperm adjust their swimming path toward the egg. In past years, many components of chemotactic signaling have been identified. Moreover, kinetic spectroscopy and imaging techniques unraveled the sequence of cellular events controlling swimming behavior. During navigation in a chemical gradient, sperm perform a surprising variety of computational operations. Here we discuss theoretical concepts of navigation strategies and the cellular underpinnings." @default.
- W1967965852 created "2016-06-24" @default.
- W1967965852 creator A5004950209 @default.
- W1967965852 creator A5027797078 @default.
- W1967965852 creator A5037998768 @default.
- W1967965852 creator A5074338260 @default.
- W1967965852 date "2014-03-01" @default.
- W1967965852 modified "2023-10-14" @default.
- W1967965852 title "The computational sperm cell" @default.
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- W1967965852 doi "https://doi.org/10.1016/j.tcb.2013.10.004" @default.
- W1967965852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24342435" @default.
- W1967965852 hasPublicationYear "2014" @default.