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- W1967965954 abstract "The design of a trial of primary prevention of hypertension in pregnancy rests on both the ability to identify women who are at risk and the definition of a clinically important outcome. The risk of developing antepartum hypertension can now be assessed nonivasively by the midpoint of pregnancy. However, maternal hypertension is not always associated with a clinically important adverse outcome for either mother or infant. The purpose of this study was to prospectively assess whether increasing risk of antepartum hypertension is associated with increasing rates of clinically important maternal and/or infant morbidity. We assembled a prospective cohort of 720 women with singleton pregnancies. The proportion of pregnancies complicated by both antepartum hypertension and maternal and/or infant morbidity increased significantly between low, moderate, and high risk groups (0.2, 6 and 58.8%, respectively, p < 0.0001). We conclude that a trial of primary prevention of hypertension in pregnancy should include a measure of significant morbidity in mother and infant." @default.
- W1967965954 created "2016-06-24" @default.
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- W1967965954 date "1990-01-01" @default.
- W1967965954 modified "2023-09-23" @default.
- W1967965954 title "The clinical significance of predictions based on screening second trimester mean arterial pressure: Adverse material and infant outcomes" @default.
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- W1967965954 doi "https://doi.org/10.1016/0895-4356(90)90174-n" @default.
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