FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967967941> ?p ?o ?g. }

• W1967967941 endingPage "381" @default.
• W1967967941 startingPage "375" @default.
• W1967967941 abstract "Nitric oxide (NO), a mediator of biological functions, has an antimicrobial activity against a variety of pathogens including viruses. In this study, we found that a constitutive, low level of inducible NO synthase (iNOS) mRNA was expressed in the EBV-infected gastric tissue-derived GT38 and GT39 cell lines, by analysis with the reverse transcription–polymerase chain reaction (RT–PCR) and Southern blotting. Treatment of these cells with a specific NOS inhibitor, NG-monomethyl-l-arginine (l-NMMA), induced the immediate-early, EBV transactivator gene BZLF1 protein ZEBRA, suggesting a significant increase in EBV reactivation by l-NMMA. Northern blotting demonstrated that BZLF1 and BRLF1 transcripts were also induced by 12-O-tetradecanoylphorbol-13 acetate (TPA). Meanwhile, constitutive expression of iNOS mRNA was inhibited by TPA. l-NMMA also enhanced TPA-induced expression of the BZLF1 gene. On the other hand, a NO donor, S-nitroso-N-acetylpenicillamine (SNAP), which releases NO in an aqueous solution, inhibited the TPA-induced BZLF1 gene expression in a dose-dependent manner at both mRNA and protein levels. These results demonstrated that NO is a regulatory factor in maintaining virus latency via inhibiting EBV reactivation in the infected epithelial cells." @default.
• W1967967941 created "2016-06-24" @default.
• W1967967941 creator A5062020822 @default.
• W1967967941 creator A5079563421 @default.
• W1967967941 creator A5089622924 @default.
• W1967967941 date "1999-06-01" @default.
• W1967967941 modified "2023-09-27" @default.
• W1967967941 title "Nitric Oxide Down-Regulates Epstein–Barr Virus Reactivation in Epithelial Cell Lines" @default.
• W1967967941 cites W1549976625 @default.
• W1967967941 cites W1588900649 @default.
• W1967967941 cites W1760923416 @default.
• W1967967941 cites W1823218897 @default.
• W1967967941 cites W1834041853 @default.
• W1967967941 cites W1841083068 @default.
• W1967967941 cites W1965408611 @default.
• W1967967941 cites W1966971174 @default.
• W1967967941 cites W1973018387 @default.
• W1967967941 cites W1984997174 @default.
• W1967967941 cites W1985148567 @default.
• W1967967941 cites W1988509745 @default.
• W1967967941 cites W1990802251 @default.
• W1967967941 cites W1992099986 @default.
• W1967967941 cites W1994527381 @default.
• W1967967941 cites W1997001042 @default.
• W1967967941 cites W2011697848 @default.
• W1967967941 cites W2037535204 @default.
• W1967967941 cites W2048635427 @default.
• W1967967941 cites W2048983335 @default.
• W1967967941 cites W2055111778 @default.
• W1967967941 cites W2058412719 @default.
• W1967967941 cites W2062434608 @default.
• W1967967941 cites W2064639670 @default.
• W1967967941 cites W2070805676 @default.
• W1967967941 cites W2073132923 @default.
• W1967967941 cites W2086484834 @default.
• W1967967941 cites W2087991196 @default.
• W1967967941 cites W2088607098 @default.
• W1967967941 cites W2101074118 @default.
• W1967967941 cites W2129588893 @default.
• W1967967941 cites W2134971124 @default.
• W1967967941 cites W2141106225 @default.
• W1967967941 cites W2146354739 @default.
• W1967967941 cites W2163444331 @default.
• W1967967941 cites W2179702494 @default.
• W1967967941 cites W2298027515 @default.
• W1967967941 cites W2342207742 @default.
• W1967967941 doi "https://doi.org/10.1006/viro.1999.9748" @default.
• W1967967941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10366574" @default.
• W1967967941 hasPublicationYear "1999" @default.
• W1967967941 type Work @default.
• W1967967941 sameAs 1967967941 @default.
• W1967967941 citedByCount "47" @default.
• W1967967941 countsByYear W19679679412012 @default.
• W1967967941 countsByYear W19679679412013 @default.
• W1967967941 countsByYear W19679679412014 @default.
• W1967967941 countsByYear W19679679412015 @default.
• W1967967941 countsByYear W19679679412016 @default.
• W1967967941 countsByYear W19679679412018 @default.
• W1967967941 countsByYear W19679679412020 @default.
• W1967967941 countsByYear W19679679412021 @default.
• W1967967941 countsByYear W19679679412022 @default.
• W1967967941 crossrefType "journal-article" @default.
• W1967967941 hasAuthorship W1967967941A5062020822 @default.
• W1967967941 hasAuthorship W1967967941A5079563421 @default.
• W1967967941 hasAuthorship W1967967941A5089622924 @default.
• W1967967941 hasBestOaLocation W19679679411 @default.
• W1967967941 hasConcept C104317684 @default.
• W1967967941 hasConcept C105580179 @default.
• W1967967941 hasConcept C1292079 @default.
• W1967967941 hasConcept C134018914 @default.
• W1967967941 hasConcept C150194340 @default.
• W1967967941 hasConcept C153911025 @default.
• W1967967941 hasConcept C159047783 @default.
• W1967967941 hasConcept C177707886 @default.
• W1967967941 hasConcept C2522874641 @default.
• W1967967941 hasConcept C2776409557 @default.
• W1967967941 hasConcept C2777468819 @default.
• W1967967941 hasConcept C2777622882 @default.
• W1967967941 hasConcept C2780727368 @default.
• W1967967941 hasConcept C2781295983 @default.
• W1967967941 hasConcept C2781375147 @default.
• W1967967941 hasConcept C515207424 @default.
• W1967967941 hasConcept C519581460 @default.
• W1967967941 hasConcept C54355233 @default.
• W1967967941 hasConcept C55493867 @default.
• W1967967941 hasConcept C81885089 @default.
• W1967967941 hasConcept C85265743 @default.
• W1967967941 hasConcept C86803240 @default.
• W1967967941 hasConceptScore W1967967941C104317684 @default.
• W1967967941 hasConceptScore W1967967941C105580179 @default.
• W1967967941 hasConceptScore W1967967941C1292079 @default.
• W1967967941 hasConceptScore W1967967941C134018914 @default.
• W1967967941 hasConceptScore W1967967941C150194340 @default.
• W1967967941 hasConceptScore W1967967941C153911025 @default.
• W1967967941 hasConceptScore W1967967941C159047783 @default.
• W1967967941 hasConceptScore W1967967941C177707886 @default.
• W1967967941 hasConceptScore W1967967941C2522874641 @default.
• W1967967941 hasConceptScore W1967967941C2776409557 @default.

• next