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• W1967996810 abstract "Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis has been recently reported as autoimmune/paraneoplastic encephalitis, affecting mostly young females.To describe opsoclonus-myoclonus syndrome in association with anti-NMDAR antibodies.Case report.Geneva University Hospital. Patient A 23-year-old woman with opsoclonus-myoclonus syndrome.Two weeks after an episode of gastroenteritis, the patient developed symptoms of depression associated with psychomotor slowing, progressive gait instability, and opsoclonus-myoclonus. Cerebrospinal fluid examination showed mild lymphocytic pleocytosis and intrathecal IgG synthesis with oligoclonal bands. The patient's condition worsened rapidly to an akinetic mutism, followed by a period of agitation, delirium, and hallucinations. These gradually subsided; however, a frontal behavior and executive dysfunction persisted 5 months after symptom presentation. No tumor was found. Anti-NMDAR antibodies were found in the cerebrospinal fluid.Opsoclonus-myoclonus may occur in patients with anti-NMDAR encephalitis. Prompt diagnosis of this disorder is important because after tumor removal and immunomodulatory therapies it has a relatively good prognosis." @default.
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• W1967996810 date "2010-01-01" @default.
• W1967996810 modified "2023-10-03" @default.
• W1967996810 title "Opsoclonus-Myoclonus Syndrome in Anti-N-Methyl-D-Aspartate Receptor Encephalitis" @default.
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• W1967996810 doi "https://doi.org/10.1001/archneurol.2009.299" @default.
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