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• W1968003737 endingPage "233" @default.
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• W1968003737 abstract "DNA polymorphisms in genes encoding apolipoproteins (apo) A-I, C-III, B and E and angiotensin-converting enzyme (ACE) have been proposed to be associated with the risk of coronary artery disease (CAD). We studied whether the same genetic markers would also be associated with the occurrence and extent of atherosclerosis in cervical arteries. DNA samples from 234 survivors of stroke or a transient ischaemic attack aged 60 years or less were examined. The presence of atherosclerosis was assessed using aortic arch angiograms. The SstI polymorphism of apoA-I/C-III gene locus, the XbaI polymorphism of apoB gene, common apoE phenotypes and the insertion/deletion polymorphism of the ACE gene were analysed. The allele frequencies of the apoA-I/C-III, apoB, apoE or ACE gene did not differ between the groups with (n = 148) or without (n = 85) cervical atherosclerosis. However, when patients with at least one apoE4 allele and one X2 allele of apoB were combined and compared with those without either of them (E2E3 or E3E3 and X1X1), a significant association with the presence of cervical atherosclerosis was found (P = 0.03). The patients having the E2E3 phenotype had a significantly elevated serum triglyceride level compared with those with the E3E3 phenotype (P = 0.03). Serum high-density lipoprotein (HDL) cholesterol was lower in the patients with the E2E3 phenotype than in those with the E3E3 and E3E4 (P = 0.01 and P = 0.06, respectively). The apoB or ACE genotypes were not significantly associated with serum lipid or lipoprotein levels. There was no association between the ACE gene polymorphism and the occurrence of hypertension. In conclusion, the interaction of common apoB and apoE alleles may increase the risk of atherosclerosis in cervical arteries." @default.
• W1968003737 created "2016-06-24" @default.
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• W1968003737 date "1998-01-01" @default.
• W1968003737 modified "2023-10-14" @default.
• W1968003737 title "Genetic risk factors and ischaemic cerebrovascular disease: role of common variation of the genes encoding apolipoproteins and angiotensin-converting enzyme" @default.
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• W1968003737 cites W1966594148 @default.
• W1968003737 cites W1968470393 @default.
• W1968003737 cites W1972120835 @default.
• W1968003737 cites W1972243699 @default.
• W1968003737 cites W1975435592 @default.
• W1968003737 cites W1977745158 @default.
• W1968003737 cites W1986340013 @default.
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• W1968003737 cites W1993252513 @default.
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• W1968003737 cites W2010165219 @default.
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• W1968003737 doi "https://doi.org/10.3109/07853899808999408" @default.
• W1968003737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9667803" @default.
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