FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968026911> ?p ?o ?g. }

• W1968026911 endingPage "278" @default.
• W1968026911 startingPage "267" @default.
• W1968026911 abstract "Although it is well established that coronary heart disease (CHD) patients with depression exhibit increased mortality compared with equally ill cardiac patients without depression, the mechanisms mediating this effect remain obscure. Depression is characterized by vulnerability to stress and heightened stress responsiveness, and stress can theoretically act through several biological pathways to contribute to excess mortality from CHD. Mechanisms connecting stress, depression and cardiovascular mortality have not been previously explored in detail. The purpose of this study was to assess the effects of stress and depression on myocardial perfusion and plasma cortisol concentrations in CHD patients. Patients with CHD with and without depression (n = 28) underwent single photon emission computed tomography imaging of myocardial perfusion at rest and during a stressful cognitive challenge. Severity of ischaemia was measured by summing perfusion defect scores across myocardial segments and subtracting out rest from stress scores. Plasma cortisol concentrations were measured at baseline and in response to the stressful challenge. There were no differences in stress-induced myocardial ischaemia or plasma cortisol response to stress between CHD patients with and without depression. Depressed CHD patients with a history of psychological trauma (n = 5) had an increase in stress-induced ischaemia scores [7; standard deviation (SD) = 5] compared with CHD patients with depression without a history of psychological trauma (2 SD = 2) and CHD patients without depression or psychological trauma (1; SD = 2) (F = 8.51; degree of freedom = 2,23; p = 0.007). Eighty per cent of CHD/depression trauma-exposed subjects had stress-induced ischaemia as opposed to 38 per cent of CHD/depression subjects without trauma exposure and 23 per cent of subjects with CHD without depression or trauma. Self-reported nervousness during the cognitive stressor was correlated with stress-induced ischaemia. These preliminary findings suggest that depression with a history of prior exposure to traumatic stress is associated with increased risk for stress-induced cardiovascular ischaemia. Copyright © 2008 John Wiley & Sons, Ltd." @default.
• W1968026911 created "2016-06-24" @default.
• W1968026911 creator A5012934310 @default.
• W1968026911 creator A5020326824 @default.
• W1968026911 creator A5029064105 @default.
• W1968026911 creator A5033948262 @default.
• W1968026911 creator A5034423123 @default.
• W1968026911 creator A5037210460 @default.
• W1968026911 creator A5047034492 @default.
• W1968026911 creator A5054714854 @default.
• W1968026911 creator A5066105118 @default.
• W1968026911 creator A5073031849 @default.
• W1968026911 creator A5078706576 @default.
• W1968026911 creator A5080890033 @default.
• W1968026911 date "2009-08-01" @default.
• W1968026911 modified "2023-10-15" @default.
• W1968026911 title "Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with depression" @default.
• W1968026911 cites W1534654728 @default.
• W1968026911 cites W1964249784 @default.
• W1968026911 cites W1965421575 @default.
• W1968026911 cites W1971828949 @default.
• W1968026911 cites W1974253960 @default.
• W1968026911 cites W1978864835 @default.
• W1968026911 cites W1979680135 @default.
• W1968026911 cites W1981459575 @default.
• W1968026911 cites W1983488763 @default.
• W1968026911 cites W1983544699 @default.
• W1968026911 cites W1994110742 @default.
• W1968026911 cites W2003313445 @default.
• W1968026911 cites W2003783857 @default.
• W1968026911 cites W2007271086 @default.
• W1968026911 cites W2013551690 @default.
• W1968026911 cites W2014381173 @default.
• W1968026911 cites W2020283909 @default.
• W1968026911 cites W2025469929 @default.
• W1968026911 cites W2035203013 @default.
• W1968026911 cites W2036891077 @default.
• W1968026911 cites W2039446174 @default.
• W1968026911 cites W2050767863 @default.
• W1968026911 cites W2051442292 @default.
• W1968026911 cites W2055310634 @default.
• W1968026911 cites W2057767273 @default.
• W1968026911 cites W2060376092 @default.
• W1968026911 cites W2066737271 @default.
• W1968026911 cites W2071480913 @default.
• W1968026911 cites W2072521482 @default.
• W1968026911 cites W2073376147 @default.
• W1968026911 cites W2080686773 @default.
• W1968026911 cites W2086049656 @default.
• W1968026911 cites W2089204188 @default.
• W1968026911 cites W2092806263 @default.
• W1968026911 cites W2101251111 @default.
• W1968026911 cites W2104386846 @default.
• W1968026911 cites W2107348072 @default.
• W1968026911 cites W2108917830 @default.
• W1968026911 cites W2112247320 @default.
• W1968026911 cites W2113929941 @default.
• W1968026911 cites W2114214919 @default.
• W1968026911 cites W2114613490 @default.
• W1968026911 cites W2140920962 @default.
• W1968026911 cites W2141141027 @default.
• W1968026911 cites W2145161166 @default.
• W1968026911 cites W2146592576 @default.
• W1968026911 cites W2150355913 @default.
• W1968026911 cites W2156234092 @default.
• W1968026911 cites W2165884492 @default.
• W1968026911 cites W2168699761 @default.
• W1968026911 cites W2321708739 @default.
• W1968026911 cites W2327061076 @default.
• W1968026911 cites W2576839150 @default.
• W1968026911 cites W2620406790 @default.
• W1968026911 cites W3161446101 @default.
• W1968026911 cites W4246386179 @default.
• W1968026911 cites W4361980610 @default.
• W1968026911 doi "https://doi.org/10.1002/smi.1246" @default.
• W1968026911 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8189292" @default.
• W1968026911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34113216" @default.
• W1968026911 hasPublicationYear "2009" @default.
• W1968026911 type Work @default.
• W1968026911 sameAs 1968026911 @default.
• W1968026911 citedByCount "15" @default.
• W1968026911 countsByYear W19680269112012 @default.
• W1968026911 countsByYear W19680269112015 @default.
• W1968026911 countsByYear W19680269112016 @default.
• W1968026911 countsByYear W19680269112018 @default.
• W1968026911 countsByYear W19680269112019 @default.
• W1968026911 countsByYear W19680269112020 @default.
• W1968026911 countsByYear W19680269112021 @default.
• W1968026911 countsByYear W19680269112023 @default.
• W1968026911 crossrefType "journal-article" @default.
• W1968026911 hasAuthorship W1968026911A5012934310 @default.
• W1968026911 hasAuthorship W1968026911A5020326824 @default.
• W1968026911 hasAuthorship W1968026911A5029064105 @default.
• W1968026911 hasAuthorship W1968026911A5033948262 @default.
• W1968026911 hasAuthorship W1968026911A5034423123 @default.
• W1968026911 hasAuthorship W1968026911A5037210460 @default.
• W1968026911 hasAuthorship W1968026911A5047034492 @default.
• W1968026911 hasAuthorship W1968026911A5054714854 @default.

• next