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- W1968045004 abstract "THE DIAGNOSIS of Neisseria meningitidis meningitis usually requires 48 to 72 hours for isolation and identification of the organism and serotyping to be performed. Determination of antimicrobial susceptibility takes an additional 24 to 48 hours. Moreover, many hospital laboratories are not equipped to perform proper sensitivity testing, resulting in further delay. Thus, these factors retard the prompt institution of specific antimicrobial chemoprophylaxis of household contacts. The choice of antibiotic depends on the serogrouping and antimicrobial sensitivity of the organism isolated from the index case. Following is a report of three patients with N meningitidis meningitis, two of whom were friends in whom the disease developed within the same week due to different serogroups. Countercurrent immunoelectrophoresis (CIE) provides a rapid and reliable method of diagnosing meningococcal meningitidis, allowing prompt and appropriate therapy for the index case and immediate antimicrobial chemoprophylaxis for household contacts. Report of Cases Case 1.— A 10-year-old girl" @default.
- W1968045004 created "2016-06-24" @default.
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- W1968045004 date "1976-10-18" @default.
- W1968045004 modified "2023-09-26" @default.
- W1968045004 title "Chemoprophylaxis Against Neisseria Meningitidis" @default.
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- W1968045004 doi "https://doi.org/10.1001/jama.1976.03270170048029" @default.
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