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- W1968053368 abstract "Purpose: Preliminary tests of drag-reducing polymer (DRP) combined with an oxygen carrier showed that the efficiency of the oxygen carrier can be increased by adding a few parts per million (ppm) of a soluble DRP. The shear stress degradation of the DRPs is important clinically since it results in a decrease in molecular weight (MW) and therefore in a decrease in activity. A novel aloe plant derived DRP, discovered in our laboratory, showed superior drag-reducing properties reducing resistance to turbulent pipe flow by over 40% at 10 ppm in a circulating flow loop compared to −20% demonstrated by a well-known DRP, high MW polyethylene oxide Polyox WSR-301 (PEO). Methods: MW, intrinsic viscosity (IV), radius of gyration (RG), and polydispersity index were determined using gel permeation chromatography with a refractive index detector, a laser light scattering detector, and a differential viscometer. Ability to resist mechanical degradation was studied using both a turbulent flow circulating loop and a cone and plate rheometer. Results: The IV and RC were significantly higher for aloe Vera polymer (AVP) than for PEO. The IV might be a good predictor of polymer drag-reducing ability and mechanical degradation resistance. AVP was shown to be more resistantto mechanical degradation than PEO following exposure to turbulent flow and other high shear stress conditions. Based on these studies, AVP shows great promise for use as a drag-reducing component of a novel artificial blood." @default.
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- W1968053368 date "2004-03-01" @default.
- W1968053368 modified "2023-10-14" @default.
- W1968053368 title "FURTHER DEVELOPMENT OF A DRAG-REDUCING COMPONENT FOR ARTIFICIAL BLOOD" @default.
- W1968053368 doi "https://doi.org/10.1097/00002480-200403000-00235" @default.
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