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- W1968082013 abstract "A capacitive immunosensor based on a self-assembled monolayer (SAM) of thiourea on gold electrode has been developed. Anti-carcinoembryonic antigen (anti-CEA) was immobilized on a self-assembled thiourea monolayer (SATUM) via covalent coupling. Under optimum conditions, the decrease in capacitive signal when carcinoembryonic antigen (CEA) standard was injected could be determined with a detection limit of 10 pg ml−1 and linearity in the range of 0.01–10 ng ml−1. The immobilized anti-CEA on SATUM gold electrode was stable and after regeneration good reproducibility of the signal could be obtained up to 45 times with an RSD lower than 3.4%. Good agreement was obtained when CEA concentrations of human serum samples determined by the flow injection capacitive immunosensor system were compared to those obtained using an enzyme linked fluorescent assay (ELFA) method (P < 0.05)." @default.
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- W1968082013 date "2006-03-01" @default.
- W1968082013 modified "2023-09-25" @default.
- W1968082013 title "A reusable capacitive immunosensor for carcinoembryonic antigen (CEA) detection using thiourea modified gold electrode" @default.
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- W1968082013 doi "https://doi.org/10.1016/j.aca.2006.01.021" @default.
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