FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968094414> ?p ?o ?g. }

• W1968094414 endingPage "1131" @default.
• W1968094414 startingPage "1123" @default.
• W1968094414 abstract "1. The effects of the volatile oil (V.O.) of the black seed (Nigella sativa) on the arterial blood pressure and heart of urethane-anaesthetized rats were investigated and the effects were compared with those of its constituent thymoquinone (T.Q.). 2. Intravenous administration of V.O. in the dose range (4-32 microliters kg.-1) or T.Q. (0.2-1.6 mg kg-1) to rats decreased the arterial blood pressure and the heart rate in a dose-dependent manner. 3. The effects of V.O. were significantly antagonized by treatment of the animals with cyproheptadine, hexamethonium atropine and by spinal pithing. 4. Treatment of the animals with reserpine (5 mg kg- 1 day-1 for 2 days) significantly antagonized the cardiovascular depressant effects induced by 4 and 8 microliters of V.O. kg-1 but not those induced by the larger doses. 5. T.Q.-induced cardiovascular depressant effects were significantly antagonized by atropine and cyproheptadine but not by reserpine. 6. The results suggested that V.O.-induced cardiovascular depressant effects were mediated mainly centrally via indirect and direct mechanisms that involved both 5-hydroxytryptaminergic and muscarinic mechanisms. The direct mechanisms may be due to the presence of T.Q. in the V.O. The V.O. seemed to possess the potential of being a potent centrally acting antihypertensive agent." @default.
• W1968094414 created "2016-06-24" @default.
• W1968094414 creator A5011661676 @default.
• W1968094414 creator A5031826268 @default.
• W1968094414 creator A5075501516 @default.
• W1968094414 date "1993-09-01" @default.
• W1968094414 modified "2023-10-17" @default.
• W1968094414 title "The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action" @default.
• W1968094414 cites W1552275448 @default.
• W1968094414 cites W1973270461 @default.
• W1968094414 cites W1976226020 @default.
• W1968094414 cites W1983251587 @default.
• W1968094414 cites W2000047622 @default.
• W1968094414 cites W2010909346 @default.
• W1968094414 cites W2015371964 @default.
• W1968094414 cites W2024231901 @default.
• W1968094414 cites W2027569438 @default.
• W1968094414 cites W2032766740 @default.
• W1968094414 cites W2043474405 @default.
• W1968094414 cites W2043739441 @default.
• W1968094414 cites W2047537362 @default.
• W1968094414 cites W2060180818 @default.
• W1968094414 cites W2082770252 @default.
• W1968094414 cites W2093645564 @default.
• W1968094414 cites W2095122837 @default.
• W1968094414 cites W2111766972 @default.
• W1968094414 cites W2172801507 @default.
• W1968094414 cites W2354817669 @default.
• W1968094414 cites W2395824169 @default.
• W1968094414 doi "https://doi.org/10.1016/0306-3623(93)90359-6" @default.
• W1968094414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8270171" @default.
• W1968094414 hasPublicationYear "1993" @default.
• W1968094414 type Work @default.
• W1968094414 sameAs 1968094414 @default.
• W1968094414 citedByCount "207" @default.
• W1968094414 countsByYear W19680944142012 @default.
• W1968094414 countsByYear W19680944142013 @default.
• W1968094414 countsByYear W19680944142014 @default.
• W1968094414 countsByYear W19680944142015 @default.
• W1968094414 countsByYear W19680944142016 @default.
• W1968094414 countsByYear W19680944142017 @default.
• W1968094414 countsByYear W19680944142018 @default.
• W1968094414 countsByYear W19680944142020 @default.
• W1968094414 countsByYear W19680944142021 @default.
• W1968094414 countsByYear W19680944142022 @default.
• W1968094414 countsByYear W19680944142023 @default.
• W1968094414 crossrefType "journal-article" @default.
• W1968094414 hasAuthorship W1968094414A5011661676 @default.
• W1968094414 hasAuthorship W1968094414A5031826268 @default.
• W1968094414 hasAuthorship W1968094414A5075501516 @default.
• W1968094414 hasConcept C134018914 @default.
• W1968094414 hasConcept C170493617 @default.
• W1968094414 hasConcept C185592680 @default.
• W1968094414 hasConcept C202751555 @default.
• W1968094414 hasConcept C2775859210 @default.
• W1968094414 hasConcept C2775864247 @default.
• W1968094414 hasConcept C2775893369 @default.
• W1968094414 hasConcept C2776120743 @default.
• W1968094414 hasConcept C2777025580 @default.
• W1968094414 hasConcept C2777842393 @default.
• W1968094414 hasConcept C2778004101 @default.
• W1968094414 hasConcept C2778206117 @default.
• W1968094414 hasConcept C2779034068 @default.
• W1968094414 hasConcept C2993714443 @default.
• W1968094414 hasConcept C55493867 @default.
• W1968094414 hasConcept C556039675 @default.
• W1968094414 hasConcept C71924100 @default.
• W1968094414 hasConcept C84393581 @default.
• W1968094414 hasConcept C98274493 @default.
• W1968094414 hasConceptScore W1968094414C134018914 @default.
• W1968094414 hasConceptScore W1968094414C170493617 @default.
• W1968094414 hasConceptScore W1968094414C185592680 @default.
• W1968094414 hasConceptScore W1968094414C202751555 @default.
• W1968094414 hasConceptScore W1968094414C2775859210 @default.
• W1968094414 hasConceptScore W1968094414C2775864247 @default.
• W1968094414 hasConceptScore W1968094414C2775893369 @default.
• W1968094414 hasConceptScore W1968094414C2776120743 @default.
• W1968094414 hasConceptScore W1968094414C2777025580 @default.
• W1968094414 hasConceptScore W1968094414C2777842393 @default.
• W1968094414 hasConceptScore W1968094414C2778004101 @default.
• W1968094414 hasConceptScore W1968094414C2778206117 @default.
• W1968094414 hasConceptScore W1968094414C2779034068 @default.
• W1968094414 hasConceptScore W1968094414C2993714443 @default.
• W1968094414 hasConceptScore W1968094414C55493867 @default.
• W1968094414 hasConceptScore W1968094414C556039675 @default.
• W1968094414 hasConceptScore W1968094414C71924100 @default.
• W1968094414 hasConceptScore W1968094414C84393581 @default.
• W1968094414 hasConceptScore W1968094414C98274493 @default.
• W1968094414 hasIssue "5" @default.
• W1968094414 hasLocation W19680944141 @default.
• W1968094414 hasLocation W19680944142 @default.
• W1968094414 hasOpenAccess W1968094414 @default.
• W1968094414 hasPrimaryLocation W19680944141 @default.
• W1968094414 hasRelatedWork W1968094414 @default.
• W1968094414 hasRelatedWork W1989642113 @default.
• W1968094414 hasRelatedWork W2002667146 @default.
• W1968094414 hasRelatedWork W2289457167 @default.
• W1968094414 hasRelatedWork W2345958810 @default.

• next