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- W196810481 abstract "Compatibility of pol yvinyl pyrollidone (PVP) and hydroxypropyl methyl cellulose (HPMC) has been investigated by solution vi scometric, ultrasonic, differential scanning calorimetric (DSC) methods and fourier transform infrared spectroscopic (FTIR) techniques. Ultrasonic velocity and adiabatic compressibility versus blend composition are plotted and found to be linear. The results obtained reveal that HPMC and PVP form a miscible blends in the entire composition range. FTIR spectroscopy demonstrated that there is strong intermolecular hydrogen bonding between carbonyl group of PVP and free hydroxyl group of HPMC. I n recent years great interes t has bee n foc used on po lymeri c bl end s du e to th eir techn ological and pharm aceuti ca l applica ti on 1.2. Compatibility of a cert ain ord er is essenti al in a poly mer blend to ac hieve good th erm al, mechani ca l and chemi cal stability. T hermodynami c mi sc ibility in a po ly mer blends is due to favourabl e dis persion force interacti on between segments of component poly mer chain s. Cellulos ics/sy ntheti c poly mer bl end s are studi ed as models for strong intermolec ul ar interac ti ons such as hydroge n bonding. The indi vidual co mponents, HPM C and PVP have bee n bee n used in drug deli very st udi e }.4 Though th ere are several publicati ons on interac ti on of PV P with organ ic and inorga ni c sys tems in bl ends and so lutions with spec ific objecti ves. The interac ti ons involving blending of HPMC with a proton donor po lymer PV P has not been studi ed so far. Hence, as a pa rt of th e research programme on sy nthes i s, charac teri zati on and appli ca ti ons of poly meri c materi als 5 - 7 , herein mi sc ible blend sys tem of HPMC and PV P is being reported and an att empt has bee n made to study th e interac ti on in volved in blending HPMC with a proton donal' po ly mer PV P." @default.
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- W196810481 date "2002-07-01" @default.
- W196810481 modified "2023-09-24" @default.
- W196810481 title "Studies on the miscibility of hydroxy propyl methyl cellulose and poly(vinyl pyrollidone) blends" @default.
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