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- W1968127419 abstract "The oxygen supply of free, Ca-alginate entrapped and microencapsulated mycelia of Penicillium raistrickii i 477 capable of 15α-hydroxylation of 13-ethyl-gon-4-en-3,17-dione was investigated. Using an oxygen microelectrode distinct gradients of oxygen within the Ca-alginate beads as well as the microcapsules were detected. Slope and width of the gradients were investigated in dependence on the kind of immobilization, the culture age and the cell density on or in the carrier as well as the different forms of the oxygen supply in the medium. So it could be shown that large parts of immobilizates, approximately 96% of the diameter of both types, were oxygen-free. In comparison with free mycelia, the lower oxygen supply of the immobilized mycelia led to a metabolic shift to fermentative catabolism." @default.
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- W1968127419 date "1993-01-01" @default.
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- W1968127419 title "Investigations of the oxygen supply in Ca-alginate beads and microcapsules loaded withPenicillium raistrickii using a microelectrode" @default.
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- W1968127419 doi "https://doi.org/10.1002/jobm.3620330506" @default.
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