FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968145514> ?p ?o ?g. }

• W1968145514 endingPage "10" @default.
• W1968145514 startingPage "1" @default.
• W1968145514 abstract "In the premature infant, periventricular leukomalacia, usually related to hypoxic-ischemic white matter damage, is the main cause of neurological impairment. We hypothesized that protracted prenatal hypoxia might induce white matter damage during the perinatal period. Pregnant Sparague-Dawley rats were placed in a chamber supplied with hypoxic gas (10% O2 -90% N2) from embryonic day 5(E5) to E20. Neonatal rat brains were investigated by histology, immunocytochemistry, western blotting, in situ hybridization, DNA fragmentation analysis, and in vivo magnetic resonance imaging (MRI). Body weight of pups subjected to prenatal hypoxia was 10 to 30% lower from p0 to P14 than in controls. Specific white matter cysts wear detected between p0 and p7 in pups subjected to prenatal hypoxia, in addition to abnormal extra-cellular matrix, increased lipid peroxidation, white matter cell death detected by TUNEL and increased activated macrophage counts in white matter. Subsequently, gliotic scars and delayed myelination primarily involving immature oligodendrocytes were seen In vivo MRI with T1, T2, and diffusion sequences disclosed similar findings immediately after birth, showing strong correlations with histological abnormalities. We speculate that protracted prenatal hypoxia in rat induces abnormalities. We speculate that protracted prenatal hypoxia in rat induces white matter damage occurring through local inflammatory response and oxidative stress linked to re-oxygenation during the perinatal period." @default.
• W1968145514 created "2016-06-24" @default.
• W1968145514 creator A5006409586 @default.
• W1968145514 creator A5011322392 @default.
• W1968145514 creator A5015000765 @default.
• W1968145514 creator A5024962818 @default.
• W1968145514 creator A5029264039 @default.
• W1968145514 creator A5033474449 @default.
• W1968145514 creator A5040760838 @default.
• W1968145514 creator A5045751065 @default.
• W1968145514 creator A5090205696 @default.
• W1968145514 date "2004-01-01" @default.
• W1968145514 modified "2023-09-25" @default.
• W1968145514 title "Gestational Hypoxia Induces White Matter Damage in Neonatal Rats: A New Model of Periventricular Leukomalacia" @default.
• W1968145514 cites W1972439039 @default.
• W1968145514 cites W1977678763 @default.
• W1968145514 cites W2000547934 @default.
• W1968145514 cites W2002716720 @default.
• W1968145514 cites W2017975056 @default.
• W1968145514 cites W2018904881 @default.
• W1968145514 cites W2019260069 @default.
• W1968145514 cites W2022431707 @default.
• W1968145514 cites W2023118429 @default.
• W1968145514 cites W2040034259 @default.
• W1968145514 cites W2059550812 @default.
• W1968145514 cites W2073305247 @default.
• W1968145514 cites W2074457825 @default.
• W1968145514 cites W2076322290 @default.
• W1968145514 cites W2077550185 @default.
• W1968145514 cites W2078546348 @default.
• W1968145514 cites W2084381185 @default.
• W1968145514 cites W2090559563 @default.
• W1968145514 cites W2095211496 @default.
• W1968145514 cites W2101606792 @default.
• W1968145514 cites W2105277370 @default.
• W1968145514 cites W2107625098 @default.
• W1968145514 cites W2112112672 @default.
• W1968145514 cites W2120787848 @default.
• W1968145514 cites W2123355863 @default.
• W1968145514 cites W2128637331 @default.
• W1968145514 cites W2132572236 @default.
• W1968145514 cites W2136811877 @default.
• W1968145514 cites W2146317119 @default.
• W1968145514 cites W2150608467 @default.
• W1968145514 cites W2167586650 @default.
• W1968145514 cites W2172078283 @default.
• W1968145514 cites W4239644696 @default.
• W1968145514 doi "https://doi.org/10.1111/j.1750-3639.2004.tb00492.x" @default.
• W1968145514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8095946" @default.
• W1968145514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14997932" @default.
• W1968145514 hasPublicationYear "2004" @default.
• W1968145514 type Work @default.
• W1968145514 sameAs 1968145514 @default.
• W1968145514 citedByCount "109" @default.
• W1968145514 countsByYear W19681455142012 @default.
• W1968145514 countsByYear W19681455142013 @default.
• W1968145514 countsByYear W19681455142014 @default.
• W1968145514 countsByYear W19681455142015 @default.
• W1968145514 countsByYear W19681455142016 @default.
• W1968145514 countsByYear W19681455142017 @default.
• W1968145514 countsByYear W19681455142018 @default.
• W1968145514 countsByYear W19681455142019 @default.
• W1968145514 countsByYear W19681455142020 @default.
• W1968145514 countsByYear W19681455142021 @default.
• W1968145514 countsByYear W19681455142022 @default.
• W1968145514 crossrefType "journal-article" @default.
• W1968145514 hasAuthorship W1968145514A5006409586 @default.
• W1968145514 hasAuthorship W1968145514A5011322392 @default.
• W1968145514 hasAuthorship W1968145514A5015000765 @default.
• W1968145514 hasAuthorship W1968145514A5024962818 @default.
• W1968145514 hasAuthorship W1968145514A5029264039 @default.
• W1968145514 hasAuthorship W1968145514A5033474449 @default.
• W1968145514 hasAuthorship W1968145514A5040760838 @default.
• W1968145514 hasAuthorship W1968145514A5045751065 @default.
• W1968145514 hasAuthorship W1968145514A5090205696 @default.
• W1968145514 hasBestOaLocation W19681455141 @default.
• W1968145514 hasConcept C126322002 @default.
• W1968145514 hasConcept C126838900 @default.
• W1968145514 hasConcept C134018914 @default.
• W1968145514 hasConcept C142724271 @default.
• W1968145514 hasConcept C143409427 @default.
• W1968145514 hasConcept C178790620 @default.
• W1968145514 hasConcept C185592680 @default.
• W1968145514 hasConcept C2778376644 @default.
• W1968145514 hasConcept C2779234561 @default.
• W1968145514 hasConcept C2780123866 @default.
• W1968145514 hasConcept C2781192897 @default.
• W1968145514 hasConcept C2781458332 @default.
• W1968145514 hasConcept C540031477 @default.
• W1968145514 hasConcept C54355233 @default.
• W1968145514 hasConcept C71924100 @default.
• W1968145514 hasConcept C7836513 @default.
• W1968145514 hasConcept C86803240 @default.
• W1968145514 hasConceptScore W1968145514C126322002 @default.
• W1968145514 hasConceptScore W1968145514C126838900 @default.
• W1968145514 hasConceptScore W1968145514C134018914 @default.
• W1968145514 hasConceptScore W1968145514C142724271 @default.
• W1968145514 hasConceptScore W1968145514C143409427 @default.

• next