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- W1968165784 abstract "In the present study, andrographolide (Andro, 1) derivatives were screened to identify potent inhibitors against tumor-cell migration and invasion, and associated structure-activity relationships were studied. Compared to 1, compounds 8a-8d exhibited more potent activities against migration in SGC-7901, PC-3, A549, HT-29 and Ec109 cell lines. Improved activities against tumor-cell migration and invasion were proved to be associated with the down-regulation of MMPs." @default.
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- W1968165784 date "2013-12-01" @default.
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- W1968165784 title "Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide" @default.
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- W1968165784 doi "https://doi.org/10.1016/j.bmcl.2013.09.049" @default.
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