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- W1968171431 abstract "• A feasibility study was undertaken prospectively to identify early clinical and laboratory factors predictive of acute hospital mortality in patients with the acquired immunodeficiency syndrome and concurrent<i>Pneumocystis carinii</i>pneumonia. Twentysix patients hospitalized with bronchoscopy-proved<i>P carinii</i>pneumonia were studied. Nineteen patients survived their episode of<i>P carinii</i>pneumonia, while 7 subjects did not. The only clinical factor associated with mortality was a history of a shorter duration of pulmonary symptoms. Univariate analysis showed decreased total CD8 cell count, total lymphocyte count, serum hemoglobin, serum albumin, total thyroxine, and total triiodothyronine values consistent with a poor outcome. Multivariate logistic regression analysis showed that the single best prognostic indicator of acute mortality appeared to be a total serum triiodothyronine value less than 0.70 nmol/L obtained early in the hospital course, and that the combination of serum triiodothyronine and hemoglobin values provided a better indication for survival. These preliminary observations would appear to justify the further exploration of serial serum triiodothyronine measurements as a potentially valuable prognostic indicator for the treatment of patients with acquired immunodeficiency syndrome infected with P carinii and possibly other intercurrent infectious illnesses. (<i>Arch Intern Med</i>. 1990;150:406-409)" @default.
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- W1968171431 date "1990-02-01" @default.
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- W1968171431 title "Serum Triiodothyronine Values" @default.
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- W1968171431 doi "https://doi.org/10.1001/archinte.1990.00390140110024" @default.
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